R P Easmann, D E Steflik, D H Pashley, R V McKinney, G M Whitford
{"title":"氟化钠诱导大鼠胃黏膜表面变化的扫描电镜研究。","authors":"R P Easmann, D E Steflik, D H Pashley, R V McKinney, G M Whitford","doi":"10.1111/j.1600-0714.1984.tb01423.x","DOIUrl":null,"url":null,"abstract":"<p><p>This paper describes the ultrastructural, topographical changes seen in rat gastric mucosa following application of 0.1 N HCl or 1, 10 or 50 mM NaF in 0.1 N HCl to the stomach. No morphological differences were noticed between the 0.1 N HCl (control) and 1 mM NaF in 0.1 N HCl specimens. Ten milliomolar NaF in 0.1 N HCl produced some desquamation of surface mucous epithelial cells while 50 mM NaF produced extensive damage to cells surrounding the gastric gland openings (foveolae) as well as interfoveolar cell loss.</p>","PeriodicalId":16672,"journal":{"name":"Journal of oral pathology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1984-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0714.1984.tb01423.x","citationCount":"22","resultStr":"{\"title\":\"Surface changes in rat gastric mucosa induced by sodium fluoride: a scanning electron microscopic study.\",\"authors\":\"R P Easmann, D E Steflik, D H Pashley, R V McKinney, G M Whitford\",\"doi\":\"10.1111/j.1600-0714.1984.tb01423.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This paper describes the ultrastructural, topographical changes seen in rat gastric mucosa following application of 0.1 N HCl or 1, 10 or 50 mM NaF in 0.1 N HCl to the stomach. No morphological differences were noticed between the 0.1 N HCl (control) and 1 mM NaF in 0.1 N HCl specimens. Ten milliomolar NaF in 0.1 N HCl produced some desquamation of surface mucous epithelial cells while 50 mM NaF produced extensive damage to cells surrounding the gastric gland openings (foveolae) as well as interfoveolar cell loss.</p>\",\"PeriodicalId\":16672,\"journal\":{\"name\":\"Journal of oral pathology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1984-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1600-0714.1984.tb01423.x\",\"citationCount\":\"22\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of oral pathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/j.1600-0714.1984.tb01423.x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of oral pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1600-0714.1984.tb01423.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
摘要
本文描述了0.1盐酸或0.1盐酸中1,10或50 mM NaF对胃的超微结构和地形变化。0.1 N HCl(对照)和1 mM NaF在0.1 N HCl标本中没有形态学差异。在0.1 N HCl中，10毫摩尔NaF可引起表面粘膜上皮细胞部分脱屑，而50毫米NaF可引起胃腺开口周围细胞(凹窝)的广泛损伤以及凹窝间细胞的损失。
Surface changes in rat gastric mucosa induced by sodium fluoride: a scanning electron microscopic study.
This paper describes the ultrastructural, topographical changes seen in rat gastric mucosa following application of 0.1 N HCl or 1, 10 or 50 mM NaF in 0.1 N HCl to the stomach. No morphological differences were noticed between the 0.1 N HCl (control) and 1 mM NaF in 0.1 N HCl specimens. Ten milliomolar NaF in 0.1 N HCl produced some desquamation of surface mucous epithelial cells while 50 mM NaF produced extensive damage to cells surrounding the gastric gland openings (foveolae) as well as interfoveolar cell loss.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
