G Sassolas, J P Boissel, R Cohen, P Chatelain, S Laporte, J Galleyrand, H Cohen, S Ferry, P Maire
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[Somatocrinin (GRF) stimulates the liberation of biologically active somatotropin (GH) in adult man].
Intravenous injection of four doses (75, 150, 300, 600 micrograms) of synthetic somatocrinin (GRF 44) greatly increases serum growth hormone concentrations in ten adult normal men in contrast to placebo. Mean peak values were identical. Plasma GH released under GRF stimulation was able to stimulate proliferation of NB2 cells.
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