[血型抗原可能是免疫过敏药物复合物与红细胞反应的受体]。

Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie Pub Date : 1983-01-01

B Habibi, Y Bretagne

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引用次数: 0

摘要

针对11种不同药物的19种抗体在药物存在下针对一组红细胞(包括普通和公共负表型)进行了广泛的测试。高发病率的血型抗原被证明是几种药物-抗体复合物的特异性受体，从而证明红细胞在药物诱导的免疫性溶血性贫血中扮演的不仅仅是“无辜的旁观者”角色。

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[Blood group antigens may be the receptors for immunoallergic drug complexes reacting with erythrocytes].

19 antibodies specific for 11 different drugs were extensively tested in the presence of the drug against a panel of red cells including common and public minus phenotypes. High incidence blood group antigens were shown to be specific receptors for several drug-antibody complexes proving thereby that red blood cells play more than an "innocent bystander" role in drug induced immune hemolytic anemias.

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Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie

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