梅毒兔血清对兔细胞体外DNA合成的抑制作用。

The British Journal of Venereal Diseases Pub Date : 1984-10-01 DOI:10.1136/sti.60.5.285

G H Wong, B Steiner, R Strugnell, S Faine, S Graves

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引用次数: 0

摘要

先前描述的与梅毒螺旋体(尼科尔斯)相关的毒性因子，在梅毒兔睾丸提取物中发现，现在也在梅毒兔血清中检测到。该毒性因子可抑制体外培养的幼兔生殖器官(BRGO)细胞的DNA合成，在感染梅毒T后30天仍存在于兔血清中。

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Inhibitory effect of syphilitic rabbit serum on DNA synthesis in rabbit cells in vitro.

A previously described toxic factor associated with Treponema pallidum (Nichols) and found in extracts of syphilitic rabbit testes has now also been detected in syphilitic rabbit serum. The toxic factor, which inhibits DNA synthesis in baby rabbit genital organ (BRGO) cells in vitro, is present in rabbit serum up to 30 days after infection with T pallidum.

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The British Journal of Venereal Diseases

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