[结节病患者肺泡液中血管紧张素I转换酶浓度升高]。

Biomedicine / [publiee pour l'A.A.I.C.I.G.] Pub Date : 1981-10-01

F C Baumann, G M Stanislas-Leguern, M S Mordelet-Dambrine, G J Huchon, J H Marsac, J P Andreux, J Chrétien

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摘要

本文测定了14例健康对照者和45例累及纵隔和肺部结节病患者血清(SACE)和支气管肺泡灌洗液(LACE)中血管紧张素转换酶(ACE)的含量。结节病组SACE浓度为4466 +/- 2202 U × 100 ml-1(平均+/- SD)，结节病组为2470 +/- 547 U × 100 ml-1(平均+/- SD)， 2470 +/- 547 U。对照100 ml-1。蕾丝浓度为65.2 +/- 48.4 U。100 ml-1和21.1 +/- 14.7 U。结节病和对照组分别为100 ml-1。这些结果支持结节病的肺泡内ACE分泌。相比于SACE, LACE可作为评价结节病肺活动性的更好的标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Increased concentration of angiotensin I converting enzyme in the alveolar fluid of patients with sarcoidosis].

Angiotensin converting enzyme (ACE) was assayed both in serum (SACE) and in bronchoalveolar fluid lavage (LACE) in 14 healthy controls and in 45 patients with sarcoidosis with mediastinal and pulmonary involvement. Concentration of SACE was 4466 +/- 2202 U x 100 ml-1 (mean +/- SD) in sarcoidosis and 2470 +/- 547 U x 100 ml-1 (chi +/- SD) in sarcoidosis and 2470 +/- 547 U . 100 ml-1 in controls. Concentrations of LACE were 65.2 +/- 48.4 U . 100 ml-1 and 21.1 +/- 14.7 U . 100 ml-1 respectively in sarcoidosis and in controls. These results are in favor of an intraalveolar secretion of ACE in sarcoidosis. LACE could be a better criterium than SACE for the evaluation of the pulmonary activity of sarcoidosis.

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Biomedicine / [publiee pour l'A.A.I.C.I.G.]

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