{"title":"与单克隆和多克隆免疫球蛋白水平升高相关过程中的血清蛋白。","authors":"L Jakab, S Fekete, K Cseh, S Benedek","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The sera of patients with IgG-myeloma, IgM-macroglobulinaemia and with processes accompanied by high polyclonal Ig-levels were measured by radial immunodiffusion for immunoglobulins, coeruloplasmin, alpha-2-macroglobulin, C3-component, transferrin, alpha-1-antitrypsin, alpha-2-haptoglobin and haemopexin. In the presence of typical changes in the immunoglobulin concentrations, elevation of alpha-2-macroglobulin was found only if polyclonal Ig was increased. The concentration of the C3 component was reduced only in IgM macroglobulinaemia, that of transferrin only in IgG-myeloma, that of alpha-2-haptoglobin only in IgM-macroglobulinaemia and in case of increased polyclonal Ig.</p>","PeriodicalId":7041,"journal":{"name":"Acta medica Academiae Scientiarum Hungaricae","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Serum proteins in processes associated with an increase in the monoclonal and polyclonal immunoglobulin levels.\",\"authors\":\"L Jakab, S Fekete, K Cseh, S Benedek\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The sera of patients with IgG-myeloma, IgM-macroglobulinaemia and with processes accompanied by high polyclonal Ig-levels were measured by radial immunodiffusion for immunoglobulins, coeruloplasmin, alpha-2-macroglobulin, C3-component, transferrin, alpha-1-antitrypsin, alpha-2-haptoglobin and haemopexin. In the presence of typical changes in the immunoglobulin concentrations, elevation of alpha-2-macroglobulin was found only if polyclonal Ig was increased. The concentration of the C3 component was reduced only in IgM macroglobulinaemia, that of transferrin only in IgG-myeloma, that of alpha-2-haptoglobin only in IgM-macroglobulinaemia and in case of increased polyclonal Ig.</p>\",\"PeriodicalId\":7041,\"journal\":{\"name\":\"Acta medica Academiae Scientiarum Hungaricae\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta medica Academiae Scientiarum Hungaricae\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta medica Academiae Scientiarum Hungaricae","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Serum proteins in processes associated with an increase in the monoclonal and polyclonal immunoglobulin levels.
The sera of patients with IgG-myeloma, IgM-macroglobulinaemia and with processes accompanied by high polyclonal Ig-levels were measured by radial immunodiffusion for immunoglobulins, coeruloplasmin, alpha-2-macroglobulin, C3-component, transferrin, alpha-1-antitrypsin, alpha-2-haptoglobin and haemopexin. In the presence of typical changes in the immunoglobulin concentrations, elevation of alpha-2-macroglobulin was found only if polyclonal Ig was increased. The concentration of the C3 component was reduced only in IgM macroglobulinaemia, that of transferrin only in IgG-myeloma, that of alpha-2-haptoglobin only in IgM-macroglobulinaemia and in case of increased polyclonal Ig.