老年人精神药理学

William M. Petrie, Thomas A. Ban
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引用次数: 2

摘要

1.1. 三环类抗抑郁药物在老年人中的应用受到其抗胆碱能和心血管作用的限制。较新的化合物,如米安色林、马普罗替林和曲扎酮可能在这方面具有优势。在控制躁动和/或精神病方面,抗精神病药和β受体阻滞剂已被成功使用。脑血管舒张剂、代谢增强剂和神经肽已被研究过,但它们在治疗老年精神病患者中的地位尚未明确确立。双氢麦角毒素已被广泛证明对阿尔茨海默型老年痴呆患者有显著的益处。胆碱能系统可能在记忆中起重要作用,尽管有关胆碱能药物治疗效果的发现是一致的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Psychopharmacology for the elderly

  • 1.

    1. The use of tricyclic antidepressant agents in the elderly is limited by their anticholinergic and cardiovascular action. Newer compounds, such as mianserin, maprotiline and trazadone may provide advantages in this respect.

  • 2.

    2. In the control of agitation and/or psychosis antipsychotic and β-blockers have been successfully employed.

  • 3.

    3. Cerebral vasodilators, metabolic enhancers, and neuropeptides have been studied but their place in the treatment of psychogeriatric patients has not been clearly established.

  • 4.

    4. Dihydroergotoxine has been extensively documented as providing significant benefit to patients with senile dementia of the Alzheimer type.

  • 5.

    5. The cholinergic system may serve important functions in memory, although findings about the therapeutic effect of cholinergic agents are consistent.

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