{"title":"鸡败菌支原体诱导鸡关节炎的发病机制。","authors":"J M Lamas da Silva, H E Adler","doi":"10.1177/030098586900600502","DOIUrl":null,"url":null,"abstract":"Gross and microscopic changes of the joint, heart, and brain were studied in chickens infected intravenously with M. gallisepticum (S6 isolate). Synovitis occurred within 3 days, followed by suppurative arthritis at 7 days, and osteomyelitis 5 days later. The pathologic changes were attributed to a severe vasculitis characterized by extensive fibrinoid necrosis and endothelial swelling. Ischemic change was observed in the heart and brain as a result of the acute arteritis.","PeriodicalId":78533,"journal":{"name":"Pathologia veterinaria","volume":"6 5","pages":"385-95"},"PeriodicalIF":0.0000,"publicationDate":"1969-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/030098586900600502","citationCount":"10","resultStr":"{\"title\":\"Pathogenesis of arthritis induced in chickens by Mycoplasma gallisepticum.\",\"authors\":\"J M Lamas da Silva, H E Adler\",\"doi\":\"10.1177/030098586900600502\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Gross and microscopic changes of the joint, heart, and brain were studied in chickens infected intravenously with M. gallisepticum (S6 isolate). Synovitis occurred within 3 days, followed by suppurative arthritis at 7 days, and osteomyelitis 5 days later. The pathologic changes were attributed to a severe vasculitis characterized by extensive fibrinoid necrosis and endothelial swelling. Ischemic change was observed in the heart and brain as a result of the acute arteritis.\",\"PeriodicalId\":78533,\"journal\":{\"name\":\"Pathologia veterinaria\",\"volume\":\"6 5\",\"pages\":\"385-95\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1969-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1177/030098586900600502\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pathologia veterinaria\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/030098586900600502\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pathologia veterinaria","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/030098586900600502","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Pathogenesis of arthritis induced in chickens by Mycoplasma gallisepticum.
Gross and microscopic changes of the joint, heart, and brain were studied in chickens infected intravenously with M. gallisepticum (S6 isolate). Synovitis occurred within 3 days, followed by suppurative arthritis at 7 days, and osteomyelitis 5 days later. The pathologic changes were attributed to a severe vasculitis characterized by extensive fibrinoid necrosis and endothelial swelling. Ischemic change was observed in the heart and brain as a result of the acute arteritis.
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