{"title":"利血平和帕格林对家兔离体虹膜3h去甲肾上腺素正常摄取率的影响","authors":"B. Herr , E. Costa","doi":"10.1016/0028-3908(69)90062-8","DOIUrl":null,"url":null,"abstract":"<div><p>The rapid uptake of<sup>3</sup>HNE exhibited<em>in vitro</em> by rabbit irises depends on the presence of sympathetic nerves and the NE concentration in the incubation medium. Pretreatment of the animals with reserpine and pargyline fails to inhibit the efficiency of this neuronal uptake process, thus confirming previous reports in the literature that the depletion of neuronal NE elicited by reserpine is not the result of the blockade of the uptake of NE by sympathetic neurons.</p></div>","PeriodicalId":14111,"journal":{"name":"International journal of neuropharmacology","volume":"8 5","pages":"Pages 463-469"},"PeriodicalIF":0.0000,"publicationDate":"1969-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0028-3908(69)90062-8","citationCount":"7","resultStr":"{\"title\":\"Normal rate of3H norepinephrine uptake by isolated iris of rabbits injected with reserpine and pargyline\",\"authors\":\"B. Herr , E. Costa\",\"doi\":\"10.1016/0028-3908(69)90062-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The rapid uptake of<sup>3</sup>HNE exhibited<em>in vitro</em> by rabbit irises depends on the presence of sympathetic nerves and the NE concentration in the incubation medium. Pretreatment of the animals with reserpine and pargyline fails to inhibit the efficiency of this neuronal uptake process, thus confirming previous reports in the literature that the depletion of neuronal NE elicited by reserpine is not the result of the blockade of the uptake of NE by sympathetic neurons.</p></div>\",\"PeriodicalId\":14111,\"journal\":{\"name\":\"International journal of neuropharmacology\",\"volume\":\"8 5\",\"pages\":\"Pages 463-469\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1969-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0028-3908(69)90062-8\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International journal of neuropharmacology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0028390869900628\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International journal of neuropharmacology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0028390869900628","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Normal rate of3H norepinephrine uptake by isolated iris of rabbits injected with reserpine and pargyline
The rapid uptake of3HNE exhibitedin vitro by rabbit irises depends on the presence of sympathetic nerves and the NE concentration in the incubation medium. Pretreatment of the animals with reserpine and pargyline fails to inhibit the efficiency of this neuronal uptake process, thus confirming previous reports in the literature that the depletion of neuronal NE elicited by reserpine is not the result of the blockade of the uptake of NE by sympathetic neurons.