茶碱缓释“洒”形式与标准糖浆制剂在幼儿哮喘中的比较研究。

Pharmatherapeutica Pub Date : 1986-01-01

K P Dawson

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引用次数: 0

摘要

61名慢性哮喘患儿接受新的缓释茶碱滴注治疗，每日2次，或茶碱液体治疗，每日4次。在三个月的研究期间，两组在依从性或症状控制方面没有可测量的差异。然而，使用喷雾剂治疗的患者副作用发生率更高，使用β激动剂雾化的比例也更高。讨论了可能的解释。

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A comparative study of theophylline in a slow-release 'sprinkle' format with a standard syrup preparation in young children with asthma.

Sixty-one chronic asthmatic children received either a new slow-release sprinkle format of theophylline, twice daily, or theophylline liquid, 4-times per day. Over a study period of three months, there was no measurable difference in compliance or symptom control between the two groups. The sprinkle-treated patients, however, had a greater incidence of side-effects and had higher rates of nebulization with beta-agonists. Possible explanations are discussed.

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Pharmatherapeutica

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