流产布鲁氏菌细胞外物质切割乳清中的牛免疫球蛋白G1。

Canadian journal of comparative medicine : Revue canadienne de medecine comparee Pub Date : 1985-07-01

K Nielsen

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引用次数: 0

摘要

体外培养的流产布鲁氏菌的培养提取物在乳清中切割一部分牛免疫球蛋白G1的Fc部分，但在血清中却没有，或者作为血清的纯化蛋白。菌株19和菌株2308的上代都能水解，而活细胞则不能。裂解过程不依赖于对B. abortus的抗体活性，似乎只需要在某些乳清样品中发现的因子，并且对其他牛免疫球蛋白无效。

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Cleavage of bovine immunoglobulin G1 in whey by an extracellular material from Brucella abortus.

Culture extracts of in vitro grown Brucella abortus were demonstrated to cleave a part of the Fc portion of bovine immunoglobulin G1 in whey but not in serum or as a purified protein from serum. Supernates from Strains 19 and 2308 of B. abortus were both capable of this hydrolysis whereas living cells were not. The cleavage process was independent of antibody activity to B. abortus, appeared to require factor(s) found only in some whey samples and was ineffective with the other bovine immunoglobulins.

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Canadian journal of comparative medicine : Revue canadienne de medecine comparee

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