褐家鼠米兰高血压品系血压遗传分析。

Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie Pub Date : 1986-12-01 DOI:10.1139/g86-134

G Schlager, B R Barber, G Bianchi

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引用次数: 16

摘要

血压水平的遗传力(h2)和控制该性状的基因座数来自两个遗传杂交，涉及大鼠米兰高血压品系及其正常血压对照。在涉及回交的遗传杂交中，估计h2 = 64%，位点数为2或3个;有证据表明，正常血压的等位基因占主导地位。在另一个只有F2的杂交中，遗传决定程度(广义遗传力)为45%，至少涉及3个位点。

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Genetic analysis of blood pressure in the Milan hypertensive strain of rat (Rattus norvegicus).

Estimates of heritability (h2) of blood pressure level and the number of loci controlling the trait were derived from two genetic crosses involving the Milan hypertensive strain of rat and its control with normal blood pressure. In the genetic cross involving backcrosses, the estimates were h2 = 64% and the number of loci was two or three; there was some evidence of dominance of the alleles for normal blood pressures. In the other cross with only F2's, the degree of genetic determination (heritability in the broad sense) was 45%, involving at least three loci.

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来源期刊

Canadian journal of genetics and cytology. Journal canadien de genetique et de cytologie

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