老龄Chbb:THOM (Wistar)大鼠定量研究。2小叶I, VIb + c和X的神经元数量。

Bibliotheca anatomica Pub Date : 1986-01-01
H Drüge, H Heinsen, Y L Heinsen
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引用次数: 0

摘要

在6- 34月龄Chbb:THOM (Wistar)大鼠中,浦肯野细胞、星状/篮状细胞、颗粒细胞和大高尔基体细胞的总数既没有性别特异性差异,也没有与年龄相关的减少。颗粒细胞的细胞密度随着年龄的增长而下降,除非考虑个体收缩因素、颗粒层的长期生长和区域差异,否则被认为是估计细胞总数的不可靠参数。与浦肯野细胞相比,颗粒状、星状/篮状和大高尔基细胞的数量存在区域差异。从这些数值上的差异可以预期局部小脑回路的生理差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quantitative studies in ageing Chbb:THOM (Wistar) rats. II. Neuron numbers in lobules I, VIb + c and X.

In 6- to 34-month-old Chbb:THOM (Wistar) rats, Purkinje, stellate/basket, granule and large Golgi cells exhibited neither sex-specific differences nor an age-related decrease in their total number. Cell density of granule cells decreased with advancing age and is regarded as an unreliable parameter for the estimation of total cell number unless individual shrinkage factors, protracted growth of the granular layer, and regional differences are taken into account as well. Regional differences were found in the number of granule, stellate/basket and large Golgi cells in relation to Purkinje cells. Differences in the physiology of local cerebellar circuits are expected from these numerical differences.

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