{"title":"新鲜分离的A组链球菌在血琼脂上反复传代。2对依从能力的影响。","authors":"A Stjernquist-Desatnik, D N Kurl, P Christensen","doi":"10.1111/j.1699-0463.1986.tb03075.x","DOIUrl":null,"url":null,"abstract":"<p><p>Group A streptococcal strains (three T-type 1, two T-type 2 and three T-type 4), freshly isolated from throat cultures, were subjected to 25 serial passages on blood agar. All strains changed their M protein production and/or opacity factor (OF)-activity during the passages. The capacity of each strain to adhere to a pool of buccal cells from six healthy individuals was studied both before and after passage. Five of six strains with decreased OF-activity/M protein production diminished significantly in adherence capacity, whereas one of two strains with increasing OF-activity adhered better to the epithelial cells. The results are discussed in relation to the clinical view of asymptomatic carriers of group A streptococci.</p>","PeriodicalId":7045,"journal":{"name":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","volume":"94 6","pages":"405-8"},"PeriodicalIF":0.0000,"publicationDate":"1986-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03075.x","citationCount":"4","resultStr":"{\"title\":\"Repeated passage of freshly isolated group A streptococci on blood agar. II. Effect on adherence capacity.\",\"authors\":\"A Stjernquist-Desatnik, D N Kurl, P Christensen\",\"doi\":\"10.1111/j.1699-0463.1986.tb03075.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Group A streptococcal strains (three T-type 1, two T-type 2 and three T-type 4), freshly isolated from throat cultures, were subjected to 25 serial passages on blood agar. All strains changed their M protein production and/or opacity factor (OF)-activity during the passages. The capacity of each strain to adhere to a pool of buccal cells from six healthy individuals was studied both before and after passage. Five of six strains with decreased OF-activity/M protein production diminished significantly in adherence capacity, whereas one of two strains with increasing OF-activity adhered better to the epithelial cells. The results are discussed in relation to the clinical view of asymptomatic carriers of group A streptococci.</p>\",\"PeriodicalId\":7045,\"journal\":{\"name\":\"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology\",\"volume\":\"94 6\",\"pages\":\"405-8\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1986-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1699-0463.1986.tb03075.x\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/j.1699-0463.1986.tb03075.x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta pathologica, microbiologica, et immunologica Scandinavica. Section B, Microbiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1699-0463.1986.tb03075.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Repeated passage of freshly isolated group A streptococci on blood agar. II. Effect on adherence capacity.
Group A streptococcal strains (three T-type 1, two T-type 2 and three T-type 4), freshly isolated from throat cultures, were subjected to 25 serial passages on blood agar. All strains changed their M protein production and/or opacity factor (OF)-activity during the passages. The capacity of each strain to adhere to a pool of buccal cells from six healthy individuals was studied both before and after passage. Five of six strains with decreased OF-activity/M protein production diminished significantly in adherence capacity, whereas one of two strains with increasing OF-activity adhered better to the epithelial cells. The results are discussed in relation to the clinical view of asymptomatic carriers of group A streptococci.