SLO4对白细胞迁移抑制因子及DTH反应的影响。

Journal of immunopharmacology Pub Date : 1986-01-01 DOI:10.3109/08923978609031089

C Vanderhoven, M Douet, K Mitchell, Y Page, J P Girard

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引用次数: 0

摘要

本I期研究证明了健康志愿者口服SLO4的免疫刺激特性。SLO4可增强DTH(延迟型超敏反应)测试的反应，并刺激参与该反应的MIF(迁移抑制因子)的产生。这些特性可能与先前证明的SLO4对干扰素的诱导有关。

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Influence of SLO4 on the leucocyte migration inhibiting factor and on the DTH response.

This phase I study demonstrates the immunostimulating properties of SLO4 administered by the oral route in the healthy volunteer. Responses to the test of DTH (delayed type hypersensitivity) were enhanced by SLO4 and the production of MIF (migration inhibiting factor) involved in this response was stimulated. These properties could be correlated with the previously demonstrated induction of interferon by SLO4.

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Journal of immunopharmacology

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