A Vachon, V Roman, C Lecomte, G Folcher, M Fatôme, P Braquet, F Berleur
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A radioprotector: cysteamine, inhibits oxygen transport in lipidic membranes.
Spin labeling techniques make possible the observation of oxygen diffusion or concentrations in phospholipid membranes. In such a system, cysteamine, depending upon the molecular cysteamine/DPPC ratio and the pH conditions, inhibits oxygen transport, and this result provides an original explanation for cellular hypoxia after cysteamine administration.
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