H I Atrah, T Sheehan, J Gribben, R J Crawford, J R O'Donnel, G P Sandilands
{"title":"白血病hla免疫患者静脉免疫球蛋白治疗后血小板输注增量的改善。","authors":"H I Atrah, T Sheehan, J Gribben, R J Crawford, J R O'Donnel, G P Sandilands","doi":"10.1111/j.1600-0609.1986.tb00821.x","DOIUrl":null,"url":null,"abstract":"<p><p>3 patients with acute leukaemia, HLA antibodies and thrombocytopenia refractory to random donor platelet transfusions were treated with high-dose i.v. immunoglobulin. All 3 patients responded favourably with improved post-transfusion recovery of random platelets. In 1 patient, the recovery of transfused histocompatible platelets was also enhanced. Treatment was followed by reduction in the total lymphocyte count and marked changes in lymphocyte subsets in 1 patient.</p>","PeriodicalId":21489,"journal":{"name":"Scandinavian journal of haematology","volume":"36 2","pages":"160-4"},"PeriodicalIF":0.0000,"publicationDate":"1986-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1600-0609.1986.tb00821.x","citationCount":"14","resultStr":"{\"title\":\"Improvement of post platelet transfusion increments following intravenous immunoglobulin therapy for leukaemic HLA-immunized patients.\",\"authors\":\"H I Atrah, T Sheehan, J Gribben, R J Crawford, J R O'Donnel, G P Sandilands\",\"doi\":\"10.1111/j.1600-0609.1986.tb00821.x\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>3 patients with acute leukaemia, HLA antibodies and thrombocytopenia refractory to random donor platelet transfusions were treated with high-dose i.v. immunoglobulin. All 3 patients responded favourably with improved post-transfusion recovery of random platelets. In 1 patient, the recovery of transfused histocompatible platelets was also enhanced. Treatment was followed by reduction in the total lymphocyte count and marked changes in lymphocyte subsets in 1 patient.</p>\",\"PeriodicalId\":21489,\"journal\":{\"name\":\"Scandinavian journal of haematology\",\"volume\":\"36 2\",\"pages\":\"160-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1986-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1111/j.1600-0609.1986.tb00821.x\",\"citationCount\":\"14\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Scandinavian journal of haematology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1111/j.1600-0609.1986.tb00821.x\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Scandinavian journal of haematology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/j.1600-0609.1986.tb00821.x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Improvement of post platelet transfusion increments following intravenous immunoglobulin therapy for leukaemic HLA-immunized patients.
3 patients with acute leukaemia, HLA antibodies and thrombocytopenia refractory to random donor platelet transfusions were treated with high-dose i.v. immunoglobulin. All 3 patients responded favourably with improved post-transfusion recovery of random platelets. In 1 patient, the recovery of transfused histocompatible platelets was also enhanced. Treatment was followed by reduction in the total lymphocyte count and marked changes in lymphocyte subsets in 1 patient.
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