实时连续血糖监测和个性化数字健康指导对2型糖尿病及前驱糖尿病患者血糖控制和生活方式的影响

IF 2.3 4区医学 Q3 ENDOCRINOLOGY & METABOLISM

Primary Care Diabetes Pub Date : 2026-02-01 Epub Date: 2025-12-13 DOI:10.1016/j.pcd.2025.12.002

Yujin Park , Hye Rin Choi , Ji-eun Lee , Boram Choi , Chang-bo Noh , Jae-Heon Kang , Ye Seul Bae

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引用次数: 0

摘要

目的：本研究评估实时连续血糖监测（CGM）结合个性化数字健康指导对2型糖尿病（T2DM）及前驱糖尿病患者血糖控制和生活方式行为的影响。方法：一项前瞻性队列研究，涉及110名来自慢性疾病管理服务的参与者。参与者接受了为期8周的干预，其中CGM数据用于提供实时反馈，并辅以个性化的生活方式指导。基线和干预后数据包括空腹血糖（FBG）、糖化血红蛋白（HbA1c）、体重指数（BMI）和生活方式因素，如体力活动和饮食习惯。根据血糖偏移的平均幅度（MAGE）将参与者分为四位数，以评估血糖变异性（GV）水平干预的效果。结果：所有受试者的血糖控制均有显著改善。GV最高组（T3）的HbA1c（7.39 %至6.82 %,p = 0.004）和FBG的降低幅度最大。T3组的身体活动得分显著提高（p = 0.005），所有受试者在干预后都报告了更健康的饮食习惯。结论：CGM与个性化数字健康指导的整合与血糖控制和生活方式行为的显着短期改善有关，特别是在GV高的个体中。

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Impact of real-time continuous glucose monitoring and personalized digital health coaching on glycemic control and lifestyle in patients with type 2 diabetes and prediabetes

Objective

This study evaluated the impact of real-time continuous glucose monitoring (CGM) combined with personalized digital health coaching on glycemic control and lifestyle behaviors in individuals with type 2 diabetes (T2DM) and prediabetes.

Method

A prospective cohort study was conducted involving 110 participants recruited from a chronic disease management service. The participants underwent an 8-week intervention where CGM data were used to provide real-time feedback, complemented by personalized lifestyle coaching. Baseline and post-intervention data included fasting blood glucose (FBG), glycated hemoglobin (HbA1c), body mass index (BMI), and lifestyle factors such as physical activity and eating habits. Participants were divided into tertiles based on mean amplitude of glycemic excursion (MAGE) to evaluate the effects of the intervention by glycemic variability (GV) level.

Results

Significant improvements in glycemic control were observed across all tertiles. The highest GV group (T3) showed the greatest reductions in HbA1c (7.39 % to 6.82 %, p = 0.004) and FBG. The physical activity scores significantly increased in the T3 group (p = 0.005), and all tertiles reported healthier dietary habits following the intervention.

Conclusions

The integration of CGM with personalized digital health coaching was associated with significant short-term improvements in glycemic control and lifestyle behaviors, particularly among individuals with high GV.

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来源期刊

Primary Care Diabetes ENDOCRINOLOGY & METABOLISM-PRIMARY HEALTH CARE

CiteScore

5.00

自引率

3.40%

发文量

134

审稿时长

47 days

期刊介绍： The journal publishes original research articles and high quality reviews in the fields of clinical care, diabetes education, nutrition, health services, psychosocial research and epidemiology and other areas as far as is relevant for diabetology in a primary-care setting. The purpose of the journal is to encourage interdisciplinary research and discussion between all those who are involved in primary diabetes care on an international level. The Journal also publishes news and articles concerning the policies and activities of Primary Care Diabetes Europe and reflects the society''s aim of improving the care for people with diabetes mellitus within the primary-care setting.