The Differentially Expressed Genes That Are Associated With Autophagy in Microtia.

The microtia is a congenital disease that might be simultaneously influenced by internal genetic level disorder and external hazardous substances. Since autophagy is an essential cell response to adverse conditions, its dysregulation has been found to be closely linked to a number of illnesses. In comparison, the role of genes that are related to autophagy in the pathogenesis of microtia is relatively rarely discussed. In the meanwhile, the study aims to determine the degree of expression and subsequent molecular pathways of autophagy-related genes and demonstrate the possible role autophagy may play in the pathophysiology of microtia. The method of computational bioinformatics analysis offers fresh perspectives and original motivations for further research in linked fields.