Ambili R Nath, Sonia Mary Thomas, Betsy Jose, Lillykutty Pothen, Jessy Mathew Mangalathil
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High-Grade Non-Hodgkin Lymphoma, Diffuse Large B-Cell Lymphoma Type Masquerading as Thyroid Malignancy and Inflammatory Breast Carcinoma: A Case Report.
This case report describes a 75-year-old female who presented with generalized tiredness and neck swelling, initially raising suspicion of a primary thyroid malignancy. Fine-needle aspiration of the thyroid nodule was suspicious for malignancy (Bethesda Category V). Further evaluation revealed an inflammatory mass lesion in the right breast which was clinically diagnosed as inflammatory carcinoma and multiple enlarged lymph nodes including axillary, cervical, supraclavicular, and inguinal nodes. Immunocytochemistry on fine needle aspiration cytology (FNAC) and biopsies and immunohistochemistry of the breast lesion and lymph nodes in the patient ultimately revealed disseminated High-Grade Non-Hodgkin Lymphoma (NHL), Diffuse Large B-Cell Lymphoma (DLBCL) type. This case highlights the diagnostic challenges linked to atypical presentations of lymphoma mimicking other primary malignancies of solid organs.
期刊介绍：
Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
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