Modification of chitosan nanoparticle by a new oxime compound: synthesis, characterization, and antioxidant activities

As an antioxidant biopolymer, chitosan nanoparticles can be conjugated with other antioxidant agents to increase the potential applications of the resulting materials in a variety of sectors, including food, packaging, cosmetics, and other industries. In this research, terephthaldialdehyde was used to quickly create a novel oxime. The oxime was then connected to chitosan nanoparticles (CSNP) to acquire established biological characteristics. FTIR, ¹H and ¹³C NMR all demonstrated the oxime’s production. The Schiff base of oxime on chitosan nanoparticles (CSNP-OX) was detected by FTIR, UV-Vis, DLS, FE-SEM-EDX, and TEM. The antioxidant activities of the CSNP and CSNP-OX were also analyzed; DPPH radical scavenging of CSNP-OX was higher than CSNP. These findings suggest that the CSNP-OX is a viable option for utilization in pharmaceuticals and food items for innovative uses.