Chandrashekhar M Wavikar, Mamta N Tanna, Gargi C Wavikar, Chandrashekhar B Kale, Maninder Singh Setia
{"title":"主动流体系统超声乳化术中iop20和iop50的术后疗效比较：随机单盲试验。","authors":"Chandrashekhar M Wavikar, Mamta N Tanna, Gargi C Wavikar, Chandrashekhar B Kale, Maninder Singh Setia","doi":"10.2147/OPTH.S542284","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare the central corneal thickness, mitigation events, post-operative vision, and complications in patients who underwent cataract surgery using the CENTURION <sup>®</sup> Vision System with the ACTIVE SENTRY <sup>®</sup> (Alcon Industries, Inc.) system and were assigned to one of two groups: intraocular pressure (IOP) group 20 or 50.</p><p><strong>Setting: </strong>Wavikar Eye Institute, Thane, India.</p><p><strong>Design: </strong>A prospective comparative two arm, randomized, single blinded, interventional study.</p><p><strong>Methods: </strong>A total of 107 eyes were randomized to either the IOP-20 (n=55) or IOP-50 (n=52) group. All patients underwent phacoemulsification with an active fluidics system performed by a single surgeon; intraocular pressure (IOP) was set at either 20 or 50 mmHg.</p><p><strong>Results: </strong>The mean [SD] baseline CCT in the IOP-20 group was 511.9 [35.7] μm and it was 521.1 [34.8] μm in the IOP 50 group (p=0.18). It had changed to 530.6 [39.8] μm in the IOP-20 group and 539.5 [39.2] μm in the IOP 50 (p=0.24). The mean [SD] ECD at the end of day 90 was 2423.0 [204.6] cells/mm<sup>2</sup> in the IOP-20 group and 2476.1 [236.0] cells/mm<sup>2</sup> in the IOP-50 group (p=0.22). Approximately 22% of the eyes in the IOP-20 group and 77% of the eyes in the IOP-50 group required active surge mitigation; this difference was statistically significant (p<0.001).</p><p><strong>Conclusion: </strong>We found that the phacoemulsification with an active fluidics system handpiece at 20 mmHg provided a safe and stable environment for cataract surgery.</p>","PeriodicalId":93945,"journal":{"name":"Clinical ophthalmology (Auckland, N.Z.)","volume":"19 ","pages":"3573-3582"},"PeriodicalIF":0.0000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495955/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparison of Post-Operative Outcomes between IOP-20 and IOP-50 in Phacoemulsification with Active Fluidics System: Randomized Single Blinded Trial.\",\"authors\":\"Chandrashekhar M Wavikar, Mamta N Tanna, Gargi C Wavikar, Chandrashekhar B Kale, Maninder Singh Setia\",\"doi\":\"10.2147/OPTH.S542284\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To compare the central corneal thickness, mitigation events, post-operative vision, and complications in patients who underwent cataract surgery using the CENTURION <sup>®</sup> Vision System with the ACTIVE SENTRY <sup>®</sup> (Alcon Industries, Inc.) system and were assigned to one of two groups: intraocular pressure (IOP) group 20 or 50.</p><p><strong>Setting: </strong>Wavikar Eye Institute, Thane, India.</p><p><strong>Design: </strong>A prospective comparative two arm, randomized, single blinded, interventional study.</p><p><strong>Methods: </strong>A total of 107 eyes were randomized to either the IOP-20 (n=55) or IOP-50 (n=52) group. All patients underwent phacoemulsification with an active fluidics system performed by a single surgeon; intraocular pressure (IOP) was set at either 20 or 50 mmHg.</p><p><strong>Results: </strong>The mean [SD] baseline CCT in the IOP-20 group was 511.9 [35.7] μm and it was 521.1 [34.8] μm in the IOP 50 group (p=0.18). It had changed to 530.6 [39.8] μm in the IOP-20 group and 539.5 [39.2] μm in the IOP 50 (p=0.24). The mean [SD] ECD at the end of day 90 was 2423.0 [204.6] cells/mm<sup>2</sup> in the IOP-20 group and 2476.1 [236.0] cells/mm<sup>2</sup> in the IOP-50 group (p=0.22). Approximately 22% of the eyes in the IOP-20 group and 77% of the eyes in the IOP-50 group required active surge mitigation; this difference was statistically significant (p<0.001).</p><p><strong>Conclusion: </strong>We found that the phacoemulsification with an active fluidics system handpiece at 20 mmHg provided a safe and stable environment for cataract surgery.</p>\",\"PeriodicalId\":93945,\"journal\":{\"name\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"volume\":\"19 \",\"pages\":\"3573-3582\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12495955/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical ophthalmology (Auckland, N.Z.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2147/OPTH.S542284\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical ophthalmology (Auckland, N.Z.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2147/OPTH.S542284","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of Post-Operative Outcomes between IOP-20 and IOP-50 in Phacoemulsification with Active Fluidics System: Randomized Single Blinded Trial.
Purpose: To compare the central corneal thickness, mitigation events, post-operative vision, and complications in patients who underwent cataract surgery using the CENTURION ® Vision System with the ACTIVE SENTRY ® (Alcon Industries, Inc.) system and were assigned to one of two groups: intraocular pressure (IOP) group 20 or 50.
Setting: Wavikar Eye Institute, Thane, India.
Design: A prospective comparative two arm, randomized, single blinded, interventional study.
Methods: A total of 107 eyes were randomized to either the IOP-20 (n=55) or IOP-50 (n=52) group. All patients underwent phacoemulsification with an active fluidics system performed by a single surgeon; intraocular pressure (IOP) was set at either 20 or 50 mmHg.
Results: The mean [SD] baseline CCT in the IOP-20 group was 511.9 [35.7] μm and it was 521.1 [34.8] μm in the IOP 50 group (p=0.18). It had changed to 530.6 [39.8] μm in the IOP-20 group and 539.5 [39.2] μm in the IOP 50 (p=0.24). The mean [SD] ECD at the end of day 90 was 2423.0 [204.6] cells/mm2 in the IOP-20 group and 2476.1 [236.0] cells/mm2 in the IOP-50 group (p=0.22). Approximately 22% of the eyes in the IOP-20 group and 77% of the eyes in the IOP-50 group required active surge mitigation; this difference was statistically significant (p<0.001).
Conclusion: We found that the phacoemulsification with an active fluidics system handpiece at 20 mmHg provided a safe and stable environment for cataract surgery.
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