{"title":"一种新型MOF结合虚拟分子印迹聚合物纸基比色传感器，配备智能手机检测器，用于灵敏、便携式和现场检测有机磷农药。","authors":"Yuqing Wang, Jiaxin Chen, Yutong Liu, Ruizhen Zhang, Jing Hong, Yunli Zhao","doi":"10.1007/s00604-025-07552-9","DOIUrl":null,"url":null,"abstract":"<div><p> A novel paper-based colorimetric sensor was synthesized based on a core–shell metal–organic framework (MOF) coated with dummy molecularly imprinted polymer (DMIP) for detecting organophosphorus pesticides (OPs). The MOF, used as the core, enhances sensor sensitivity owing to its inherent advantages such as high catalytic activity and stability; meanwhile, the introduction of MIP effectively overcomes the limitation of MOFs in single-substrate detection. This sensor shows great on-site detection potential and superior analytical performance owing to the combination of color response and quantitative analysis via a smartphone. Six OPs were successfully detected in agricultural products with a limit of detection as low as 0.5 ng/mL. Moreover, the consistency between the sensor and HPLC–MS/MS results was verified, yielding satisfactory agreement ranging from 94.4% to 100%. In conclusion, this method is promising for portable, rapid, and on-site food safety detection.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":705,"journal":{"name":"Microchimica Acta","volume":"192 11","pages":""},"PeriodicalIF":5.3000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A novel MOF combined with dummy molecularly imprinted polymer paper-based colorimetric sensor equipped with a smartphone detector for sensitive, portable, and on-site detection of organophosphorus pesticides\",\"authors\":\"Yuqing Wang, Jiaxin Chen, Yutong Liu, Ruizhen Zhang, Jing Hong, Yunli Zhao\",\"doi\":\"10.1007/s00604-025-07552-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p> A novel paper-based colorimetric sensor was synthesized based on a core–shell metal–organic framework (MOF) coated with dummy molecularly imprinted polymer (DMIP) for detecting organophosphorus pesticides (OPs). The MOF, used as the core, enhances sensor sensitivity owing to its inherent advantages such as high catalytic activity and stability; meanwhile, the introduction of MIP effectively overcomes the limitation of MOFs in single-substrate detection. This sensor shows great on-site detection potential and superior analytical performance owing to the combination of color response and quantitative analysis via a smartphone. Six OPs were successfully detected in agricultural products with a limit of detection as low as 0.5 ng/mL. Moreover, the consistency between the sensor and HPLC–MS/MS results was verified, yielding satisfactory agreement ranging from 94.4% to 100%. In conclusion, this method is promising for portable, rapid, and on-site food safety detection.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":705,\"journal\":{\"name\":\"Microchimica Acta\",\"volume\":\"192 11\",\"pages\":\"\"},\"PeriodicalIF\":5.3000,\"publicationDate\":\"2025-10-04\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Microchimica Acta\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00604-025-07552-9\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Microchimica Acta","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00604-025-07552-9","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
A novel MOF combined with dummy molecularly imprinted polymer paper-based colorimetric sensor equipped with a smartphone detector for sensitive, portable, and on-site detection of organophosphorus pesticides
A novel paper-based colorimetric sensor was synthesized based on a core–shell metal–organic framework (MOF) coated with dummy molecularly imprinted polymer (DMIP) for detecting organophosphorus pesticides (OPs). The MOF, used as the core, enhances sensor sensitivity owing to its inherent advantages such as high catalytic activity and stability; meanwhile, the introduction of MIP effectively overcomes the limitation of MOFs in single-substrate detection. This sensor shows great on-site detection potential and superior analytical performance owing to the combination of color response and quantitative analysis via a smartphone. Six OPs were successfully detected in agricultural products with a limit of detection as low as 0.5 ng/mL. Moreover, the consistency between the sensor and HPLC–MS/MS results was verified, yielding satisfactory agreement ranging from 94.4% to 100%. In conclusion, this method is promising for portable, rapid, and on-site food safety detection.
期刊介绍：
As a peer-reviewed journal for analytical sciences and technologies on the micro- and nanoscale, Microchimica Acta has established itself as a premier forum for truly novel approaches in chemical and biochemical analysis. Coverage includes methods and devices that provide expedient solutions to the most contemporary demands in this area. Examples are point-of-care technologies, wearable (bio)sensors, in-vivo-monitoring, micro/nanomotors and materials based on synthetic biology as well as biomedical imaging and targeting.
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