免疫性血小板减少性紫癜患者类固醇诱导的Takotsubo心肌病

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Clinical Case Reports Pub Date : 2025-10-03 DOI:10.1002/ccr3.71047

Qutaiba Qafisheh, Roaa Aljunaidi, Abdalhakim Shubietah, Mohammed AbuBaha, Hossam Salameh, Muath Baniowda, Mohanad Qwaider, Mohammad Alqadi, Imad Hariri

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引用次数: 0

摘要

本病例报告强调了地塞米松给药与Takotsubo心肌病发病之间的时间关系，强调了认识到药物制剂是潜在的非传统触发因素的重要性，特别是在患有潜在心血管疾病且没有可识别的情绪或身体压力源的患者中。诊断倾向于地塞米松触发的Takotsubo表型，基于非阻塞性冠状动脉，超出单一动脉区域的区域壁运动异常，缺乏交替应激源，以及类固醇介导的儿茶酚胺能上调的生物学合理性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Steroid-Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura

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Steroid-Induced Takotsubo Cardiomyopathy in a Patient With Immune Thrombocytopenic Purpura

This case report highlights a temporal relationship between dexamethasone administration and the onset of Takotsubo cardiomyopathy, underscoring the importance of recognizing pharmacologic agents as potential non-traditional triggers, particularly in patients with underlying cardiovascular disease and no identifiable emotional or physical stressors. Diagnosis favored a dexamethasone-triggered Takotsubo phenotype based on non-obstructive coronaries, regional wall-motion abnormalities extending beyond a single arterial territory, absence of alternate stressors, and biologic plausibility of steroid-mediated catecholaminergic upregulation.

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来源期刊

Clinical Case Reports MEDICINE, GENERAL & INTERNAL-

自引率

14.30%

发文量

1268

审稿时长

13 weeks

期刊介绍： Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).