使用神经成像技术量化脑不对称的方法学考虑

IF 2.6 4区医学 Q3 NEUROSCIENCES

Brain Research Pub Date : 2025-10-01 DOI:10.1016/j.brainres.2025.149979

Haokun Li , Jingli Qu , Gaolang Gong

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引用次数: 0

摘要

结构和功能上的不对称对于理解人类大脑左右半球之间的关系至关重要。量化大脑不对称或侧化是该领域的基本方法选择，不同研究的方法差异很大。这篇综述旨在简要总结和讨论在不同的神经成像技术和研究背景下量化大脑不对称的方法学考虑。我们说明了特定同伦单位的定义如何作为先决条件，如何使用侧化指数公式量化这些单位之间的半球不对称程度，以及这些侧化指数的应用如何需要仔细考虑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Methodological considerations for quantifying brain asymmetry using neuroimaging techniques

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Methodological considerations for quantifying brain asymmetry using neuroimaging techniques

Structural and functional asymmetries are crucial for understanding the relationship between the left and right hemispheres of the human brain. Quantifying brain asymmetry or lateralization represents a fundamental methodological choice in this field, and approaches vary considerably across studies. This review aims to briefly summarize and discuss methodological considerations for quantifying brain asymmetry across different neuroimaging techniques and research contexts. We illustrate how the definition of specific homotopic units serves as a prerequisite, how the degree of hemispheric asymmetry between these units is quantified using lateralization index formulas, and how the application of these lateralization indices requires careful consideration.

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来源期刊

Brain Research 医学-神经科学

CiteScore

5.90

自引率

3.40%

发文量

268

审稿时长

47 days

期刊介绍： An international multidisciplinary journal devoted to fundamental research in the brain sciences. Brain Research publishes papers reporting interdisciplinary investigations of nervous system structure and function that are of general interest to the international community of neuroscientists. As is evident from the journals name, its scope is broad, ranging from cellular and molecular studies through systems neuroscience, cognition and disease. Invited reviews are also published; suggestions for and inquiries about potential reviews are welcomed. With the appearance of the final issue of the 2011 subscription, Vol. 67/1-2 (24 June 2011), Brain Research Reviews has ceased publication as a distinct journal separate from Brain Research. Review articles accepted for Brain Research are now published in that journal.