缺血性中风后小胶质细胞-星形胶质细胞串扰。

IF 2.9 3区 医学 Q2 NEUROSCIENCES
Shangsong Yang, Yuxiong Chen, Jialin Tang, Yicheng Cui, Wei Wei, Zhongnan Hao, Zhipeng Xiao, Yongli Pan, Qinyuan Tian, Wenqiang Xin, Meihua Li
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引用次数: 0

摘要

缺血性中风是最常见的中风形式,因其高发病率、致残率和死亡率严重影响人类健康。缺血性脑卒中复杂的病理反应涉及多种细胞和组织的相互作用。其中星形胶质细胞和小胶质细胞作为神经系统的重要组成部分,在缺血性卒中的病理过程中起着重要作用。除了它们各自的功能外,越来越多的研究表明星形胶质细胞和小胶质细胞之间的相互作用在缺血性卒中后至关重要。整合目前的研究报告,研究和阐明缺血性卒中后小胶质细胞和星形胶质细胞相互作用对神经系统的影响,旨在为未来的学术研究和疾病治疗提供新的见解和方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microglia-astrocyte crosstalk following ischemic stroke.

Ischemic stroke, the most prevalent form of stroke, severely impacts human health due to its high incidence, disability, and mortality rates. The complex pathological response to ischemic stroke involves the interplay of various cells and tissues. Among these, astrocytes and microglia, as essential components of nervous system, play significant roles in the pathological processes of ischemic stroke. In addition to their individual functions, an increasing number of studies have revealed that the interaction between astrocytes and microglia is crucial following ischemic stroke. It integrates current research reports to examine and clarify the effects of interaction between the microglia and astrocytes on the nervous system after ischemic stroke, aiming to provide new insights and approaches for future academic research and disease treatment.

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来源期刊
Molecular Brain
Molecular Brain NEUROSCIENCES-
CiteScore
7.30
自引率
0.00%
发文量
97
审稿时长
>12 weeks
期刊介绍: Molecular Brain is an open access, peer-reviewed journal that considers manuscripts on all aspects of studies on the nervous system at the molecular, cellular, and systems level providing a forum for scientists to communicate their findings. Molecular brain research is a rapidly expanding research field in which integrative approaches at the genetic, molecular, cellular and synaptic levels yield key information about the physiological and pathological brain. These studies involve the use of a wide range of modern techniques in molecular biology, genomics, proteomics, imaging and electrophysiology.
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