柚皮（Naringi crenulata, Roxb.）茎中的柠檬素及其它成分尼科尔森。

IF 1.6 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-09-30 DOI:10.1080/14786419.2025.2566473

Suriphon Singha, Sudarat Kruakaew, Jantana Yahuafai, Sanit Thongnest, Somyote Sutthivaiyakit

{"title":"柚皮（Naringi crenulata, Roxb.）茎中的柠檬素及其它成分尼科尔森。","authors":"Suriphon Singha, Sudarat Kruakaew, Jantana Yahuafai, Sanit Thongnest, Somyote Sutthivaiyakit","doi":"10.1080/14786419.2025.2566473","DOIUrl":null,"url":null,"abstract":"Five previously undescribed compounds including four limonoids and a phenolic glycoside as well as seven known compounds were isolated from Naringi crenulata (Roxb.) Nicolson stem. Spectroscopic data of these previously undescribed compounds are reported. The configurations at stereocenters in the isolates were based on the NOE interactions. The bio-transformations of three unusual limonoids from limonin were proposed. Selected isolates were evaluated for their growth inhibitory activities against two cancer cell lines and a Vero cell.","PeriodicalId":18990,"journal":{"name":"Natural Product Research","volume":" ","pages":"1-11"},"PeriodicalIF":1.6000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Limonoids and other constituents of the stem of Naringi crenulata (Roxb.) Nicholson.\",\"authors\":\"Suriphon Singha, Sudarat Kruakaew, Jantana Yahuafai, Sanit Thongnest, Somyote Sutthivaiyakit\",\"doi\":\"10.1080/14786419.2025.2566473\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Five previously undescribed compounds including four limonoids and a phenolic glycoside as well as seven known compounds were isolated from Naringi crenulata (Roxb.) Nicolson stem. Spectroscopic data of these previously undescribed compounds are reported. The configurations at stereocenters in the isolates were based on the NOE interactions. The bio-transformations of three unusual limonoids from limonin were proposed. Selected isolates were evaluated for their growth inhibitory activities against two cancer cell lines and a Vero cell.\",\"PeriodicalId\":18990,\"journal\":{\"name\":\"Natural Product Research\",\"volume\":\" \",\"pages\":\"1-11\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Natural Product Research\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1080/14786419.2025.2566473\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Natural Product Research","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/14786419.2025.2566473","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

摘要

从红桃Naringi crenulata （Roxb.）中分离得到5种先前未被描述的化合物，包括4种柠檬类化合物和1种酚苷类化合物，以及7种已知化合物。Nicolson干。报道了这些先前未描述的化合物的光谱数据。分离物的立体中心构型基于NOE相互作用。提出了三种罕见的柠檬素类化合物的生物转化方法。选择的分离物对两种癌细胞系和一种Vero细胞的生长抑制活性进行了评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Limonoids and other constituents of the stem of Naringi crenulata (Roxb.) Nicholson.

Five previously undescribed compounds including four limonoids and a phenolic glycoside as well as seven known compounds were isolated from Naringi crenulata (Roxb.) Nicolson stem. Spectroscopic data of these previously undescribed compounds are reported. The configurations at stereocenters in the isolates were based on the NOE interactions. The bio-transformations of three unusual limonoids from limonin were proposed. Selected isolates were evaluated for their growth inhibitory activities against two cancer cell lines and a Vero cell.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.