苦参皂苷A和B，两种新发现的苦参皂苷。

IF 1.6 3区化学 Q3 CHEMISTRY, APPLIED

Natural Product Research Pub Date : 2025-09-30 DOI:10.1080/14786419.2025.2565711

Ping Wang, Feiyu Liao, Hongqian Liu, Ruirui Zhang

引用次数: 0

摘要

reeckeacarnisides A(1)和B(2)分别从reeckea carnea (Andrews) Kunth的根中分离得到。通过理化性质和光谱学方法推导了它们的结构。采用CCK8法对3种肿瘤细胞株的细胞毒活性进行了测定，结果表明，reeckecarnide B具有抑制作用，IC50值为45.6 μM。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Reineckeacarnisides A and B, two new saponins from Reineckea carnea.

Reineckeacarnisides A (1) and B (2) were obtained from the roots of Reineckea carnea (Andrews) Kunth. Their structures were deduced by physicochemical properties and spectroscopic methods. Cytotoxic activities in three cancer cell lines were evaluated by CCK8 method and Reineckeacarniside B possessed inhibitory effect with IC₅₀ of 45.6 μM.

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来源期刊

Natural Product Research 化学-医药化学

CiteScore

5.10

自引率

9.10%

发文量

605

审稿时长

2.1 months

期刊介绍： The aim of Natural Product Research is to publish important contributions in the field of natural product chemistry. The journal covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds. The communications include coverage of work on natural substances of land and sea and of plants, microbes and animals. Discussions of structure elucidation, synthesis and experimental biosynthesis of natural products as well as developments of methods in these areas are welcomed in the journal. Finally, research papers in fields on the chemistry-biology boundary, eg. fermentation chemistry, plant tissue culture investigations etc., are accepted into the journal. Natural Product Research issues will be subtitled either ""Part A - Synthesis and Structure"" or ""Part B - Bioactive Natural Products"". for details on this , see the forthcoming articles section. All manuscript submissions are subject to initial appraisal by the Editor, and, if found suitable for further consideration, to peer review by independent, anonymous expert referees. All peer review is single blind and submission is online via ScholarOne Manuscripts.