Liang Li, Fuqiang Zhao, Xufeng Liang, Chunlin Deng, Jianxia Zhang, Tingting Chen, Yang Wang, Jin Wang, Yan Cai, Yong Yao
{"title":"基于柱状[5]芳烃的聚多巴胺-前药纳米平台,用于靶向和协同化学动力学-光热化疗癌症","authors":"Liang Li, Fuqiang Zhao, Xufeng Liang, Chunlin Deng, Jianxia Zhang, Tingting Chen, Yang Wang, Jin Wang, Yan Cai, Yong Yao","doi":"10.1039/d5cc05197e","DOIUrl":null,"url":null,"abstract":"A targeted nanoplatform was developed by formulating a polydopamine–prodrug conjugate with pillar[5]arene (P5PDA/DOX/Fe-Fa-Py), achieving potent antitumor activity through a targeted and synergistic combination of chemodynamic, photothermal, and chemotherapy.","PeriodicalId":67,"journal":{"name":"Chemical Communications","volume":"54 1","pages":""},"PeriodicalIF":4.2000,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A pillar[5]arene-based polydopamine-prodrug nanoplatform for targeted and synergistic chemodynamic-photothermalchemotherapy of cancer\",\"authors\":\"Liang Li, Fuqiang Zhao, Xufeng Liang, Chunlin Deng, Jianxia Zhang, Tingting Chen, Yang Wang, Jin Wang, Yan Cai, Yong Yao\",\"doi\":\"10.1039/d5cc05197e\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A targeted nanoplatform was developed by formulating a polydopamine–prodrug conjugate with pillar[5]arene (P5PDA/DOX/Fe-Fa-Py), achieving potent antitumor activity through a targeted and synergistic combination of chemodynamic, photothermal, and chemotherapy.\",\"PeriodicalId\":67,\"journal\":{\"name\":\"Chemical Communications\",\"volume\":\"54 1\",\"pages\":\"\"},\"PeriodicalIF\":4.2000,\"publicationDate\":\"2025-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical Communications\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://doi.org/10.1039/d5cc05197e\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical Communications","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1039/d5cc05197e","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A pillar[5]arene-based polydopamine-prodrug nanoplatform for targeted and synergistic chemodynamic-photothermalchemotherapy of cancer
A targeted nanoplatform was developed by formulating a polydopamine–prodrug conjugate with pillar[5]arene (P5PDA/DOX/Fe-Fa-Py), achieving potent antitumor activity through a targeted and synergistic combination of chemodynamic, photothermal, and chemotherapy.
期刊介绍:
ChemComm (Chemical Communications) is renowned as the fastest publisher of articles providing information on new avenues of research, drawn from all the world''s major areas of chemical research.