妊娠期豚鼠子宫动脉的肽能神经支配。

Basic and applied histochemistry Pub Date : 1988-01-01
M C Mione, C Cavallotti, G Burnstock, F Amenta
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引用次数: 0

摘要

研究了妊娠对豚鼠子宫动脉多肽神经支配密度和形态的影响。采用全坐位拉伸法制备发情和孕晚期豚鼠子宫动脉,用免疫组化方法检测神经肽Y (NPY)-、血管活性肠多肽(VIP)-、降钙素基因相关肽(CGRP)-和P物质(SP)-免疫反应性神经纤维。妊娠后期,NPY-和CGRP-神经纤维密度显著降低,VIP-和SP-免疫反应神经密度中度降低。本文讨论了妊娠晚期子宫动脉中肽免疫反应神经密度降低的意义和可能的生理相关性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The peptidergic innervation of the guinea pig uterine artery in pregnancy.

The influence of pregnancy on the density and pattern of the peptidergic innervation of the guinea pig uterine artery was studied. Whole mount stretch preparations of the uterine artery from estrus and late pregnant guinea pigs were processed for the immunohistochemical demonstration of neuropeptide Y (NPY)-, vasoactive intestinal polypeptide (VIP)-, calcitonin gene-related peptide (CGRP)- and substance P (SP)- immunoreactive nerve fibres. In late pregnancy the density of NPY- and CGRP- containing nerve fibres was remarkably decreased, while that of VIP- and SP- immunoreactive nerves showed a moderate reduction. The meaning and the possible physiological relevance of the decreased density of peptide-immunoreactive nerves in the uterine artery in late pregnancy are discussed.

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