脑的比较化学解剖学:概念和方法。

Basic and applied histochemistry Pub Date : 1988-01-01
A Fasolo, G C Panzica, C Viglietti-Panzica, T Renda, L D'Este
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引用次数: 0

摘要

神经肽的研究为比较和进化研究提供了一个合适的平台。比较分析可以深入了解细胞间传播分子的保守模式,这种模式可能与一些古老的进化和细胞的限制有关。同时,它可以告诉我们调节是如何在分子,细胞,多细胞水平上发生的,以赋予物种特定的功能组织。利用脊椎动物中枢神经元系统(CNS)免疫细胞化学分析的一些例子,迄今为止获得的结果表明,一种新的比较化学神经解剖学的兴起。然而,为了理解神经肽分布的稳定性、异质性或其他走向复杂性的趋势,我们需要比较“是什么”和“为什么”的基本原理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative chemical anatomy of the brain: concepts and methods.

The study of neuropeptides represents an appropriate playground for comparative and evolutionary research. Comparative analysis can give insight into the conservative pattern of intercellular transmission molecules, possibly bound both to some evolutionary antiquity and to cellular constraints. In the same time it can teach us how modulation has occurred at molecular, cellular, multicellular levels in order to give the species-specific functional organization. Using some examples from vertebrate central neurons system (CNS) immunocytochemical analyses, the results so far obtained suggest the rise of a new comparative chemical neuroanatomy. The rationale of "what" and "why" we are comparing is, however, needed in order to understand constancy, heterogeneity or else trends toward complexity in the distribution of neuropeptides.

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