年轻高脂血症患者伴视网膜中央静脉闭塞的新生血管性青光眼。

IF 1.5 4区 医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL
Journal of International Medical Research Pub Date : 2025-09-01 Epub Date: 2025-09-24 DOI:10.1177/03000605251379254
Iden Amiri, Meredith R Klifto, Alice Yang Zhang
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引用次数: 0

摘要

本病例报告一例罕见的继发于视网膜中央静脉阻塞的新生血管性青光眼,患者为30岁出头的健康男性,表现为急性单侧视力丧失、眼痛和眼压升高。眼科成像,包括超宽视场眼底摄影和光学相干断层扫描,显示视网膜出血、视网膜内积液和虹膜新生血管形成,与缺血性视网膜中央静脉闭塞和继发性新生血管性青光眼一致。值得注意的是,系统评估显示严重的高脂血症与患者严格的非素食饮食有关,没有其他可识别的危险因素。治疗包括玻璃体内注射抗血管内皮生长因子,Ahmed青光眼瓣膜植入术,全视网膜光凝术后玻璃体切除。患者在开始降脂治疗和饮食咨询后,视力部分恢复。本病例强调了考虑可改变的代谢因素的重要性,特别是极端的饮食模式,在年轻的视网膜中央静脉闭塞患者。它支持将全身脂质筛查和饮食评估纳入非典型视网膜血管事件的诊断工作。虽然不能确定因果关系,但本病例提倡进一步研究饮食相关高脂血症在眼部血管疾病中的全身性影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Neovascular glaucoma associated with central retinal vein occlusion in a young patient with hyperlipidemia.

Neovascular glaucoma associated with central retinal vein occlusion in a young patient with hyperlipidemia.

Neovascular glaucoma associated with central retinal vein occlusion in a young patient with hyperlipidemia.

This case report presents a rare instance of neovascular glaucoma secondary to central retinal vein occlusion in a previously healthy man in his early 30s who exhibited acute unilateral vision loss, ocular pain, and elevated intraocular pressure. Ophthalmic imaging, including ultra-widefield fundus photography and optical coherence tomography, revealed retinal hemorrhages, intraretinal fluid, and iris neovascularization consistent with ischemic central retinal vein occlusion and secondary neovascular glaucoma. Notably, systemic evaluation revealed severe hyperlipidemia associated with the patient's strict nonvegetarian diet, with no other identifiable risk factors. Treatment included intravitreal antivascular endothelial growth factor injections, Ahmed glaucoma valve implantation, and panretinal photocoagulation followed by pars plana vitrectomy. The patient experienced partial visual recovery after the initiation of lipid-lowering therapy and dietary counseling. This case underscores the importance of considering modifiable metabolic factors, particularly extreme dietary patterns, in young patients presenting with central retinal vein occlusion. It supports the incorporation of systemic lipid screening and dietary assessment into the diagnostic workup of atypical retinal vascular events. Although causality cannot be established, this case advocates the need for further investigation into the systemic implications of diet-related hyperlipidemia in ocular vascular disease.

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来源期刊
CiteScore
3.20
自引率
0.00%
发文量
555
审稿时长
1 months
期刊介绍: _Journal of International Medical Research_ is a leading international journal for rapid publication of original medical, pre-clinical and clinical research, reviews, preliminary and pilot studies on a page charge basis. As a service to authors, every article accepted by peer review will be given a full technical edit to make papers as accessible and readable to the international medical community as rapidly as possible. Once the technical edit queries have been answered to the satisfaction of the journal, the paper will be published and made available freely to everyone under a creative commons licence. Symposium proceedings, summaries of presentations or collections of medical, pre-clinical or clinical data on a specific topic are welcome for publication as supplements. Print ISSN: 0300-0605
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