T Rizzi, P Q Costa, F M Delpino, T R Flores, S Pieniz
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引用次数: 0
摘要
本研究旨在通过系统的文献综述，评价乳酸菌乳酸乳球菌（Lactococcus lactis， L. lactis）在小鼠炎症性肠病防治中的益生菌作用。在Cochrane Library和PubMed数据库中进行文献检索，以乳酸菌乳杆菌、炎症性肠病、预防、治疗、克罗恩病、溃疡性结肠炎和乳酸菌为描述词，评价乳酸菌乳杆菌对小鼠炎症性肠病的预防和治疗作用。共发现3320篇文章，其中只有6篇被纳入综述。结果表明，乳酸菌等乳酸菌可能有助于溃疡性结肠炎和克罗恩病等疾病的特征性体征和症状的治疗和肠道调节。
Probiotic effect of Lactococcus lactis genetically modified in the prevention and treatment of inflammatory bowel diseases in mice: a systematic review.
The aim of this study was to evaluate the probiotic effect of the lactic acid bacterium Lactococcus lactis (L. lactis) in the prevention and treatment of inflammatory bowel disease in mice through a systematic literature review. A literature search was conducted in the Cochrane Library and PubMed databases to evaluate the effect of the lactic acid bacterium L. lactis in the prevention and treatment of inflammatory bowel disease in mice using the descriptors: L. lactis, inflammatory bowel disease, prevention, treatment, Crohn's disease, ulcerative colitis and lactic acid bacteria. A total of 3,320 articles were found, of which only six were included in the review. The results suggest that lactic acid bacteria such as L. lactis may be helpful in the treatment and intestinal modulation of animals exhibiting characteristic signs and symptoms of diseases such as ulcerative colitis and Crohn's disease.
期刊介绍：
The BJB – Brazilian Journal of Biology® is a scientific journal devoted to publishing original articles in all fields of the Biological Sciences, i.e., General Biology, Cell Biology, Evolution, Biological Oceanography, Taxonomy, Geographic Distribution, Limnology, Aquatic Biology, Botany, Zoology, Genetics, and Ecology. Priority is given to papers presenting results of researches in the Neotropical region. Material published includes research papers, review papers (upon approval of the Editorial Board), notes, book reviews, and comments.
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