研究细胞迁移的机械代谢工具箱。

IF 8.4 2区生物学 Q1 CELL BIOLOGY

Cold Spring Harbor perspectives in biology Pub Date : 2025-09-22 DOI:10.1101/cshperspect.a041755

Katherine M Young, Santiago Lopez, Keefer Boone, Mehmet Acikel, Xavi Gallart, Cynthia Reinhart-King

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引用次数: 0

摘要

细胞迁移在很大程度上受到运动细胞本身的物理性质和细胞所处的环境的影响。除了在细胞迁移的背景下研究细胞和细胞外的力学特性外，人们对理解迁移、力学和代谢之间的交叉也越来越感兴趣。在这项工作中，我们讨论了研究人员目前在细胞迁移背景下用于研究细胞力学、细胞外力学和代谢的许多技术和方法。我们的目标是让人们接触到机械生物学和机械代谢领域的新方法，并强调通过机械透镜研究细胞迁移的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Mechanometabolism Toolbox for Studying Cell Migration.

Cell migration is greatly affected by both the physical properties of the motile cell itself and the environment through which the cell is moving. In addition to studying cellular and extracellular mechanical properties in the context of cell migration, there is a growing interest in understanding the intersection between migration, mechanics, and metabolism. In this work, we discuss the many techniques and approaches researchers are currently using to study cellular mechanics, extracellular mechanics, and metabolism in the context of cell migration. Our goal is to bring exposure to new approaches in the fields of mechanobiology and mechanometabolism and highlight the importance of studying cell migration through a mechanical lens.

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来源期刊

Cold Spring Harbor perspectives in biology CELL BIOLOGY-

CiteScore

15.00

自引率

1.40%

发文量

审稿时长

3-8 weeks

期刊介绍： Cold Spring Harbor Perspectives in Biology offers a comprehensive platform in the molecular life sciences, featuring reviews that span molecular, cell, and developmental biology, genetics, neuroscience, immunology, cancer biology, and molecular pathology. This online publication provides in-depth insights into various topics, making it a valuable resource for those engaged in diverse aspects of biological research.