见见作者：郭灿荣和Kurt w里奇

IF 7.2 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Cell Chemical Biology Pub Date : 2025-09-18 DOI:10.1016/j.chembiol.2025.08.009

Canyong Guo, Kurt Wüthrich

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引用次数: 0

摘要

在接受《细胞化学生物学》杂志主编Mishtu Dey博士的采访时，题为“腺苷2A受体平衡信号激活的结构基础依赖于变构介导的结构动力学”的文章的作者分享了他们对结构生物学技术进步的看法，以及基因标记技术的应用如何使探索GPCR的核心成为可能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Meet the authors: Canyong Guo and Kurt Wüthrich

In an interview with Dr. Mishtu Dey, Editor-in-Chief of Cell Chemical Biology, the authors of the article entitled “Structural basis of Adenosine 2A Receptor balanced signaling activation relies on allosterically mediated structural dynamics” share their thoughts on technological advances in structural biology and how applications of genetic labeling techniques made it possible to probe into the core of a GPCR.

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来源期刊

Cell Chemical Biology Biochemistry, Genetics and Molecular Biology-Molecular Medicine

CiteScore

14.70

自引率

2.30%

发文量

143

期刊介绍： Cell Chemical Biology, a Cell Press journal established in 1994 as Chemistry & Biology, focuses on publishing crucial advances in chemical biology research with broad appeal to our diverse community, spanning basic scientists to clinicians. Pioneering investigations at the chemistry-biology interface, the journal fosters collaboration between these disciplines. We encourage submissions providing significant conceptual advancements of broad interest across chemical, biological, clinical, and related fields. Particularly sought are articles utilizing chemical tools to perturb, visualize, and measure biological systems, offering unique insights into molecular mechanisms, disease biology, and therapeutics.