细胞因子释放综合征和噬血细胞综合征与免疫治疗相关:叙述性回顾。

Eric Mayor-Vázquez, Elena Cuenca Fito, Pilar Marcos-Neira, Cándido Díaz-Lagares, Carme Gomila-Sintes, Noelia Albalá, Alejandra García-Roche, Pedro Castro
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引用次数: 0

摘要

近年来,由于生存率和生活质量的提高,发达国家受血液肿瘤疾病影响的患者人数有所增加。这一增加增加了对重症监护病房(ICU)护理的更大需求,主要是由于与免疫抑制、治疗毒性或癌症本身引起的并发症有关的并发症。免疫疗法已经改变了癌症的治疗方式,但它可能会导致严重的副作用,如细胞因子释放综合征和噬血细胞综合征,这往往需要住院治疗。本综述旨在扩展ICU中这些并发症的知识和管理策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cytokine release syndrome and hemophagocytic syndrome associated with immunotherapy: A narrative review.

In recent years, there has been an increase in the number of patients affected by oncohematologic diseases in developed countries due to the improved survival rates and quality of life. This increase has generated a greater need for care in intensive care units (ICU), mainly due to complications related to immunosuppression, treatment toxicity or complications derived from cancer itself. Immunotherapy has transformed cancer treatment, but it can cause serious side effects such as cytokine release syndrome and hemophagocytic syndrome, which often require ICU admission. This review seeks to expand knowledge and management strategies for these complications in the ICU.

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