{"title":"绿色合成酰胺改性超交联吸附树脂高效分离杜仲提取物中的绿原酸","authors":"Xuefang Chen, Zhijie Shen, Haifeng Chen, Hairong Chen, Tessafa Abrham Ashagrie, Hailong Li, Hairong Zhang, Lian Xiong, Xinde Chen","doi":"10.1002/jssc.70256","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p><i>Eucommia ulmoides Oliver</i> leaf is rich in chlorogenic acid, which has antioxidant, antiviral, and anti-inflammatory activities. In this work, a new and green strategy for functional hyper-crosslinked adsorption resin based on Friedel–Crafts reaction of pendant vinyl groups in divinylbenzene with anhydrous ethanol and acrylamide grafting polymerization was developed, and the obtained HCREt-AM resin had excellent performance on chlorogenic acid separation from <i>Eucommia ulmoides Oliver</i> leaf extract. Adsorption isotherm and kinetics study showed the adsorption process fitted by Langmuir adsorption isotherm and pseudo-second-order kinetic equation. The dynamic saturated adsorption capacity of 88.0 mg·g<sup>−1</sup> was obtained, and chlorogenic acid content was raised from 7.91% to 48.27%. The pH-controlled ionization of chlorogenic acid determined the adsorption process, and π-π stacking, hydrophobic interactions, hydrogen bonding, and electrostatic interactions are the main adsorption mechanisms.</p>\n </div>","PeriodicalId":17098,"journal":{"name":"Journal of separation science","volume":"48 9","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Green Synthetic Amide-Modified Hyper-Cross-Linked Adsorption Resin for Efficiently Separating Chlorogenic Acid From Eucommia ulmoides Extracts\",\"authors\":\"Xuefang Chen, Zhijie Shen, Haifeng Chen, Hairong Chen, Tessafa Abrham Ashagrie, Hailong Li, Hairong Zhang, Lian Xiong, Xinde Chen\",\"doi\":\"10.1002/jssc.70256\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n <p><i>Eucommia ulmoides Oliver</i> leaf is rich in chlorogenic acid, which has antioxidant, antiviral, and anti-inflammatory activities. In this work, a new and green strategy for functional hyper-crosslinked adsorption resin based on Friedel–Crafts reaction of pendant vinyl groups in divinylbenzene with anhydrous ethanol and acrylamide grafting polymerization was developed, and the obtained HCREt-AM resin had excellent performance on chlorogenic acid separation from <i>Eucommia ulmoides Oliver</i> leaf extract. Adsorption isotherm and kinetics study showed the adsorption process fitted by Langmuir adsorption isotherm and pseudo-second-order kinetic equation. The dynamic saturated adsorption capacity of 88.0 mg·g<sup>−1</sup> was obtained, and chlorogenic acid content was raised from 7.91% to 48.27%. The pH-controlled ionization of chlorogenic acid determined the adsorption process, and π-π stacking, hydrophobic interactions, hydrogen bonding, and electrostatic interactions are the main adsorption mechanisms.</p>\\n </div>\",\"PeriodicalId\":17098,\"journal\":{\"name\":\"Journal of separation science\",\"volume\":\"48 9\",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-09-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of separation science\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jssc.70256\",\"RegionNum\":3,\"RegionCategory\":\"工程技术\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of separation science","FirstCategoryId":"5","ListUrlMain":"https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jssc.70256","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Green Synthetic Amide-Modified Hyper-Cross-Linked Adsorption Resin for Efficiently Separating Chlorogenic Acid From Eucommia ulmoides Extracts
Eucommia ulmoides Oliver leaf is rich in chlorogenic acid, which has antioxidant, antiviral, and anti-inflammatory activities. In this work, a new and green strategy for functional hyper-crosslinked adsorption resin based on Friedel–Crafts reaction of pendant vinyl groups in divinylbenzene with anhydrous ethanol and acrylamide grafting polymerization was developed, and the obtained HCREt-AM resin had excellent performance on chlorogenic acid separation from Eucommia ulmoides Oliver leaf extract. Adsorption isotherm and kinetics study showed the adsorption process fitted by Langmuir adsorption isotherm and pseudo-second-order kinetic equation. The dynamic saturated adsorption capacity of 88.0 mg·g−1 was obtained, and chlorogenic acid content was raised from 7.91% to 48.27%. The pH-controlled ionization of chlorogenic acid determined the adsorption process, and π-π stacking, hydrophobic interactions, hydrogen bonding, and electrostatic interactions are the main adsorption mechanisms.
期刊介绍：
The Journal of Separation Science (JSS) is the most comprehensive source in separation science, since it covers all areas of chromatographic and electrophoretic separation methods in theory and practice, both in the analytical and in the preparative mode, solid phase extraction, sample preparation, and related techniques. Manuscripts on methodological or instrumental developments, including detection aspects, in particular mass spectrometry, as well as on innovative applications will also be published. Manuscripts on hyphenation, automation, and miniaturization are particularly welcome. Pre- and post-separation facets of a total analysis may be covered as well as the underlying logic of the development or application of a method.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
