结外弥漫性大b细胞性精索淋巴瘤：沙特阿拉伯首例报道病例

IF 0.4 Q4 UROLOGY & NEPHROLOGY

Urology Case Reports Pub Date : 2025-09-04 DOI:10.1016/j.eucr.2025.103199

Basmah Z. Al Ghanim , Hussain A. Al Ghanim , Erum M. Alhumood

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引用次数: 0

摘要

原发性精索淋巴瘤是罕见的，占精索肿瘤的1.6%。典型表现为弥漫性大b细胞淋巴瘤（DLBCL），病程积极，预后差。一名53岁男性，表现为左侧睾丸肿块进展超过一年。影像显示精索肿瘤。根治性睾丸切除术和组织病理学证实为IV期结外DLBCL。患者接受了6个周期的CHOP-R化疗加上2个额外的利妥昔单抗周期，尽管病情进展，但仍获得了良好的反应。这个病例强调了早期诊断、先进的影像和多学科治疗对这种罕见的侵袭性恶性肿瘤的重要性。

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Extranodal diffuse large B-cell lymphoma of the spermatic cord: The first reported case in Saudi Arabia

Primary spermatic cord lymphoma is rare, accounting for 1.6 % of spermatic cord tumors. It typically presents as diffuse large B-cell lymphoma (DLBCL) with aggressive course and poor prognosis.

A 53-year-old male presented with progressive left testicular mass over one year. Imaging revealed spermatic cord tumor. Radical orchiectomy and histopathology confirmed stage IV Extranodal DLBCL.

Patient received 6 cycles CHOP-R chemotherapy plus 2 additional Rituximab cycles, achieving favorable response despite advanced disease.

This case emphasizes importance of early diagnosis, advanced imaging, and multidisciplinary treatment for this rare aggressive malignancy.

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