溶剂介导的深共晶结晶研究进展：面向制药和生物分子应用的绿色可调平台

IF 2.6 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

CrystEngComm Pub Date : 2025-06-24 DOI:10.1039/D5CE00434A

Jiali Yu, Yixuan Wang, Peiya Shen, Yuanfeng Wei, Yuan Gao, Jianjun Zhang, Ke Zhang and Shuai Qian

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引用次数: 0

摘要

结晶是工业中一个关键的单元操作，因为它对物质的物理化学性质有重大影响。近年来，深共晶溶剂（DESs）作为一种能够调节各种材料的成核和晶体生长的可持续介质得到了探索。本文综述了近年来DESs用于结晶的研究进展，包括它们在调控多态性、晶体习惯和共晶形成方面的作用。此外，还讨论了DESs在结晶控制中的应用面临的挑战和未来的前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Advances in deep eutectic solvent-mediated crystallization: toward green and tunable platforms for pharmaceutical and biomolecular applications

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Advances in deep eutectic solvent-mediated crystallization: toward green and tunable platforms for pharmaceutical and biomolecular applications

Crystallization is a critical unit operation in industry, as it significantly influences the physicochemical properties of substances. In recent years, deep eutectic solvents (DESs) have been explored as sustainable media capable of modulating nucleation and crystal growth of various materials. This review presents an overview of recent advances in the use of DESs for crystallization, including their roles in regulating polymorphism, crystal habit and cocrystal formation. In addition, current challenges and future perspectives on the application of DESs in crystallization control are discussed.

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