呼吸道合胞病毒和人偏肺病毒传播的决定因素。

IF 19.3 1区医学 Q1 MICROBIOLOGY

Clinical Microbiology Reviews Pub Date : 2025-08-01 DOI:10.1128/cmr.00203-24

David A Foley,David W Smith,Ian Barr,Hannah C Moore,Mark Nicol,Christopher C Blyth

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引用次数: 0

摘要

呼吸道合胞病毒和人偏肺病毒是全球呼吸道疾病的主要病因，尤其影响儿童和老年人。尽管具有临床意义，但在了解其传播的决定因素方面仍然存在重大差距。本文综述了影响RSV和hMPV传播的多方面因素，包括病毒结构和进化、宿主行为和病毒脱落动力学、环境条件对病毒存活的影响、人群和社区传播网络的作用以及SARS-CoV-2的影响。此外，我们探索预防策略，包括免疫接种和非药物干预，以减少高风险环境中的传播。

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Determinants of respiratory syncytial virus and human metapneumovirus transmission.

SUMMARYRespiratory syncytial virus and human metapneumovirus are major causes of respiratory illness globally, particularly affecting children and older adults. Despite their clinical significance, substantial gaps persist in understanding the determinants of their transmission. This review examines the multifaceted factors shaping RSV and hMPV transmission, including viral structure and evolution, host behaviors and viral shedding dynamics, the influence of environmental conditions on viral survival, the roles of population- and community-level transmission networks, and the impact of SARS-CoV-2. Additionally, we explore prevention strategies, including immunizations and non-pharmaceutical interventions, to reduce transmission in high-risk settings.

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来源期刊

Clinical Microbiology Reviews 医学-微生物学

CiteScore

54.20

自引率

0.50%

发文量

期刊介绍： Clinical Microbiology Reviews (CMR) is a journal that primarily focuses on clinical microbiology and immunology.It aims to provide readers with up-to-date information on the latest developments in these fields.CMR also presents the current state of knowledge in clinical microbiology and immunology.Additionally, the journal offers balanced and thought-provoking perspectives on controversial issues in these areas.