{"title":"代谢组学在急性呼吸窘迫综合征中的应用:综述。","authors":"Xiu-Yan Song, Hao Qin, Wei Zhang","doi":"10.1177/00368504251356317","DOIUrl":null,"url":null,"abstract":"<p><p>Acute respiratory distress syndrome (ARDS) is a clinical condition characterized by damage and inflammation of the alveolar-capillary membrane, which is associated with high incidence and mortality rates. Metabolomics, a significant field of systematic biology, provides a novel perspective for understanding the pathophysiological mechanisms underlying ARDS by analyzing small molecule metabolites in biological samples. This narrative review explores the application of metabolomics in ARDS.</p>","PeriodicalId":56061,"journal":{"name":"Science Progress","volume":"108 3","pages":"368504251356317"},"PeriodicalIF":2.9000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317215/pdf/","citationCount":"0","resultStr":"{\"title\":\"Application of metabolomics in acute respiratory distress syndrome: A narrative review.\",\"authors\":\"Xiu-Yan Song, Hao Qin, Wei Zhang\",\"doi\":\"10.1177/00368504251356317\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Acute respiratory distress syndrome (ARDS) is a clinical condition characterized by damage and inflammation of the alveolar-capillary membrane, which is associated with high incidence and mortality rates. Metabolomics, a significant field of systematic biology, provides a novel perspective for understanding the pathophysiological mechanisms underlying ARDS by analyzing small molecule metabolites in biological samples. This narrative review explores the application of metabolomics in ARDS.</p>\",\"PeriodicalId\":56061,\"journal\":{\"name\":\"Science Progress\",\"volume\":\"108 3\",\"pages\":\"368504251356317\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12317215/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Science Progress\",\"FirstCategoryId\":\"103\",\"ListUrlMain\":\"https://doi.org/10.1177/00368504251356317\",\"RegionNum\":4,\"RegionCategory\":\"综合性期刊\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/7/30 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"MULTIDISCIPLINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Science Progress","FirstCategoryId":"103","ListUrlMain":"https://doi.org/10.1177/00368504251356317","RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MULTIDISCIPLINARY SCIENCES","Score":null,"Total":0}
Application of metabolomics in acute respiratory distress syndrome: A narrative review.
Acute respiratory distress syndrome (ARDS) is a clinical condition characterized by damage and inflammation of the alveolar-capillary membrane, which is associated with high incidence and mortality rates. Metabolomics, a significant field of systematic biology, provides a novel perspective for understanding the pathophysiological mechanisms underlying ARDS by analyzing small molecule metabolites in biological samples. This narrative review explores the application of metabolomics in ARDS.
期刊介绍:
Science Progress has for over 100 years been a highly regarded review publication in science, technology and medicine. Its objective is to excite the readers'' interest in areas with which they may not be fully familiar but which could facilitate their interest, or even activity, in a cognate field.