脑深部电刺激治疗pla2g6相关性帕金森病的远期疗效1例并文献复习

IF 1.8 Q3 CLINICAL NEUROLOGY

Clinical Parkinsonism Related Disorders Pub Date : 2025-01-01 DOI:10.1016/j.prdoa.2025.100377

Takashi Tsuboi , Takashi Uematsu , Yoshiki Ito , Tomotaka Ishizaki , Satoshi Maesawa , Ryuta Saito , Hiroyo Yoshino , Nobutaka Hattori , Adolfo Ramirez-Zamora , Michael S. Okun , Masahisa Katsuno

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引用次数: 0

摘要

一名患有早发性PARK14和新型PLA2G6变异的患者接受了内苍白球深部脑刺激，实现了持续三年的运动和生活质量改善。虽然文献综述支持运动方面的益处，但本病例的认知能力下降突出了对这种罕见疾病的非运动症状和生活质量进行全面评估的必要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Long-term efficacy of deep brain stimulation in PLA2G6-related Parkinson’s disease: A case report with literature review

A patient with early-onset PARK14 and novel PLA2G6 variants underwent globus pallidus internus deep brain stimulation, achieving sustained three-year motor and quality-of-life improvements. Although a literature review supports motor benefits, our case’s cognitive decline highlights the need for comprehensive assessment of non-motor symptoms and quality-of-life in this rare disorder.

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来源期刊

Clinical Parkinsonism Related Disorders Medicine-Neurology (clinical)

CiteScore

2.70

自引率

0.00%

发文量

审稿时长

98 days