Mehrnoosh Hosseinpoor, Farideh Kazemi, Seyedeh Zahra Masoumi, Flora Tajiki, Yasaman Pakniyat, Mina Mollabashi, Hamideh Chelopaz, Seyed Mohammad Hossein Oliaei
{"title":"塔吉克方法生活方式改变咨询对POI妇女激素水平和妊娠率的影响:一项在哈马丹Fatemieh医院进行的随机对照试验。","authors":"Mehrnoosh Hosseinpoor, Farideh Kazemi, Seyedeh Zahra Masoumi, Flora Tajiki, Yasaman Pakniyat, Mina Mollabashi, Hamideh Chelopaz, Seyed Mohammad Hossein Oliaei","doi":"10.2174/0115748871366215250712150042","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Reduction in the quantity and quality of ova during the reproductive period of women is a physiological phenomenon. However, in some women, the deterioration of the ovaries occurs suddenly, and they experience infertility due to premature ovarian failure. This study aimed to explore the correlation between Primary ovarian insufficiency (POI) and the pregnancy rate of women in relation to the Tajik lifestyle modification diet.</p><p><strong>Methods: </strong>In this clinical randomized controlled trial study conducted in 2023, 72 infertile couples were randomly assigned to two groups, control and intervention. The intervention group received Tajik counseling sessions. In cases of normal distribution, the ANCOVA test was used to evaluate the difference between the two groups, and within-group comparisons were made using a paired t-test, while between-group comparisons were made using an independent t-test. A significance level of less than 0.05 was considered.</p><p><strong>Results: </strong>In comparison to the control group, women with POI exhibited notably lower levels of follicle-stimulating hormone, luteinizing hormone, and prolactin, along with higher anti mullein levels. Within the intervention group, there were 17 successful pregnancies, two miscarriages, and 14 instances of improved menstrual status, resulting in a pregnancy rate of 52.7%.</p><p><strong>Discussion: </strong>After receiving lifestyle modification advice using the Tajik method, women with POI experienced improvements in their FSH, LH, AMH, and PRL hormone levels, leading to an increase in their pregnancy rate.</p><p><strong>Conclusion: </strong>According to the results of the present study, the use of the Tajik method is recommended to help treat POI.</p>","PeriodicalId":21174,"journal":{"name":"Reviews on recent clinical trials","volume":" ","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of Lifestyle Modification Counselling by the Tajik Method on Hormonal Profiles and Pregnancy Rates in Women with POI: A Randomized Controlled Trial at Fatemieh Hospital, Hamadan, 2024.\",\"authors\":\"Mehrnoosh Hosseinpoor, Farideh Kazemi, Seyedeh Zahra Masoumi, Flora Tajiki, Yasaman Pakniyat, Mina Mollabashi, Hamideh Chelopaz, Seyed Mohammad Hossein Oliaei\",\"doi\":\"10.2174/0115748871366215250712150042\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>Reduction in the quantity and quality of ova during the reproductive period of women is a physiological phenomenon. However, in some women, the deterioration of the ovaries occurs suddenly, and they experience infertility due to premature ovarian failure. This study aimed to explore the correlation between Primary ovarian insufficiency (POI) and the pregnancy rate of women in relation to the Tajik lifestyle modification diet.</p><p><strong>Methods: </strong>In this clinical randomized controlled trial study conducted in 2023, 72 infertile couples were randomly assigned to two groups, control and intervention. The intervention group received Tajik counseling sessions. In cases of normal distribution, the ANCOVA test was used to evaluate the difference between the two groups, and within-group comparisons were made using a paired t-test, while between-group comparisons were made using an independent t-test. A significance level of less than 0.05 was considered.</p><p><strong>Results: </strong>In comparison to the control group, women with POI exhibited notably lower levels of follicle-stimulating hormone, luteinizing hormone, and prolactin, along with higher anti mullein levels. Within the intervention group, there were 17 successful pregnancies, two miscarriages, and 14 instances of improved menstrual status, resulting in a pregnancy rate of 52.7%.</p><p><strong>Discussion: </strong>After receiving lifestyle modification advice using the Tajik method, women with POI experienced improvements in their FSH, LH, AMH, and PRL hormone levels, leading to an increase in their pregnancy rate.</p><p><strong>Conclusion: </strong>According to the results of the present study, the use of the Tajik method is recommended to help treat POI.</p>\",\"PeriodicalId\":21174,\"journal\":{\"name\":\"Reviews on recent clinical trials\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Reviews on recent clinical trials\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/0115748871366215250712150042\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews on recent clinical trials","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115748871366215250712150042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
Impact of Lifestyle Modification Counselling by the Tajik Method on Hormonal Profiles and Pregnancy Rates in Women with POI: A Randomized Controlled Trial at Fatemieh Hospital, Hamadan, 2024.
Introduction: Reduction in the quantity and quality of ova during the reproductive period of women is a physiological phenomenon. However, in some women, the deterioration of the ovaries occurs suddenly, and they experience infertility due to premature ovarian failure. This study aimed to explore the correlation between Primary ovarian insufficiency (POI) and the pregnancy rate of women in relation to the Tajik lifestyle modification diet.
Methods: In this clinical randomized controlled trial study conducted in 2023, 72 infertile couples were randomly assigned to two groups, control and intervention. The intervention group received Tajik counseling sessions. In cases of normal distribution, the ANCOVA test was used to evaluate the difference between the two groups, and within-group comparisons were made using a paired t-test, while between-group comparisons were made using an independent t-test. A significance level of less than 0.05 was considered.
Results: In comparison to the control group, women with POI exhibited notably lower levels of follicle-stimulating hormone, luteinizing hormone, and prolactin, along with higher anti mullein levels. Within the intervention group, there were 17 successful pregnancies, two miscarriages, and 14 instances of improved menstrual status, resulting in a pregnancy rate of 52.7%.
Discussion: After receiving lifestyle modification advice using the Tajik method, women with POI experienced improvements in their FSH, LH, AMH, and PRL hormone levels, leading to an increase in their pregnancy rate.
Conclusion: According to the results of the present study, the use of the Tajik method is recommended to help treat POI.
期刊介绍:
Reviews on Recent Clinical Trials publishes frontier reviews on recent clinical trials of major importance. The journal"s aim is to publish the highest quality review articles in the field. Topics covered include: important Phase I – IV clinical trial studies, clinical investigations at all stages of development and therapeutics. The journal is essential reading for all researchers and clinicians involved in drug therapy and clinical trials.