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引用次数: 0
摘要
陈磊从事抗真菌耐受性和持久性的临床诊断工作。在这个影响范围内,他反思了a . Rosenberg, I. V. Ene, M. Bibi, S. Zakin等人的论文“抗真菌耐受性是一种不同于耐药性的亚群体效应,并与持久性念菌有关”(Nat Commun 9:2470, 2018, https://doi.org/10.1038/s41467-018-04926-x)和“巨噬细胞内化创造了一个耐多药的真菌持久性库,并促进了耐药性的出现”(a . Arastehfar, F. Daneshnia, N. Cabrera,S. Penalva-Lopez, et . (Nat Commun 14:11 183, 2023, https://doi.org/10.1038/s41467-023-36882-6)影响了他在抗真菌耐受性和持久性诊断方法发展方面的工作。
mSphere of Influence: Diagnosis of antifungal tolerance and persistence.
Lei Chen works in the field of clinical diagnosis of antifungal tolerance and persistence. In this mSphere of Influence, he reflects on how the papers "Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia" by A. Rosenberg, I. V. Ene, M. Bibi, S. Zakin, et al. (Nat Commun 9:2470, 2018, https://doi.org/10.1038/s41467-018-04926-x) and "Macrophage internalization creates a multidrug-tolerant fungal persister reservoir and facilitates the emergence of drug resistance" by A. Arastehfar, F. Daneshnia, N. Cabrera, S. Penalva-Lopez, et al. (Nat Commun 14:1183, 2023, https://doi.org/10.1038/s41467-023-36882-6) impacted his work on the development of diagnostic methods for antifungal tolerance and persistence.
期刊介绍:
mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.