{"title":"日本一家农场使用猪繁殖与呼吸综合征病毒商业灭活疫苗后，育肥猪死亡率降低。","authors":"Yoriko Yonezawa, Tomohiro Nakagami, Nobuyuki Tsutsumi, Nozomu Momma, Osamu Taira, Ryota Matsuyama, Kohei Makita","doi":"10.1292/jvms.24-0506","DOIUrl":null,"url":null,"abstract":"<p><p>PRRS (Porcine Reproductive and Respiratory Syndrome) is a costly disease in the global pig industry. In 2021, Nisseiken Co., Ltd. in Japan launched a PRRS-killed vaccine, PRRS-ME, but its effectiveness on reducing the death rate under field conditions remained unassessed. A longitudinal study on a PRRS-positive farm in Japan (July 2019-July 2022) evaluated its effect on death rates. Piglets on a PRRS-negative farrowing farm were vaccinated at 3 and 8 weeks of age in March 2021. The vaccinated piglets were introduced to the finisher farm, where a PRRS outbreak occurred. Vaccination coverage was not associated with the death rates of growers but was negatively associated with those of finishers. The predicted reduction in the death rate of finishers associated with complete vaccination coverage was 56.8%.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Reduction in finisher pig death rate on a farm in Japan following use of a commercial killed vaccine against porcine reproductive and respiratory syndrome virus.\",\"authors\":\"Yoriko Yonezawa, Tomohiro Nakagami, Nobuyuki Tsutsumi, Nozomu Momma, Osamu Taira, Ryota Matsuyama, Kohei Makita\",\"doi\":\"10.1292/jvms.24-0506\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>PRRS (Porcine Reproductive and Respiratory Syndrome) is a costly disease in the global pig industry. In 2021, Nisseiken Co., Ltd. in Japan launched a PRRS-killed vaccine, PRRS-ME, but its effectiveness on reducing the death rate under field conditions remained unassessed. A longitudinal study on a PRRS-positive farm in Japan (July 2019-July 2022) evaluated its effect on death rates. Piglets on a PRRS-negative farrowing farm were vaccinated at 3 and 8 weeks of age in March 2021. The vaccinated piglets were introduced to the finisher farm, where a PRRS outbreak occurred. Vaccination coverage was not associated with the death rates of growers but was negatively associated with those of finishers. The predicted reduction in the death rate of finishers associated with complete vaccination coverage was 56.8%.</p>\",\"PeriodicalId\":49959,\"journal\":{\"name\":\"Journal of Veterinary Medical Science\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-07-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Veterinary Medical Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1292/jvms.24-0506\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.24-0506","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Reduction in finisher pig death rate on a farm in Japan following use of a commercial killed vaccine against porcine reproductive and respiratory syndrome virus.
PRRS (Porcine Reproductive and Respiratory Syndrome) is a costly disease in the global pig industry. In 2021, Nisseiken Co., Ltd. in Japan launched a PRRS-killed vaccine, PRRS-ME, but its effectiveness on reducing the death rate under field conditions remained unassessed. A longitudinal study on a PRRS-positive farm in Japan (July 2019-July 2022) evaluated its effect on death rates. Piglets on a PRRS-negative farrowing farm were vaccinated at 3 and 8 weeks of age in March 2021. The vaccinated piglets were introduced to the finisher farm, where a PRRS outbreak occurred. Vaccination coverage was not associated with the death rates of growers but was negatively associated with those of finishers. The predicted reduction in the death rate of finishers associated with complete vaccination coverage was 56.8%.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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