布雷登量表对重症监护病房老年心力衰竭患者全因死亡的预后价值:一项队列研究

J L Zhu, H Pan, Z C Yang, G H Jiang, Z H Wang
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引用次数: 0

摘要

背景:心力衰竭(HF)仍然是与高死亡率相关的主要全球健康挑战。Braden量表评分(BSS)是临床最常用的评估患者压力损伤风险的工具之一,有研究报道BSS可以反映患者的虚弱状态。本研究的目的是探讨BSS是否可以预测重症监护病房(ICU)老年心力衰竭患者的短期和长期全因死亡风险。方法与结果:采用重症监护医学信息市场- iv3.0 (mimic - iv3.0)数据库中60岁及以上HF患者入院24 h内的数据进行分析。提取所需数据,数据收集期为2009 - 2023年。心衰患者的主要结局是30天和1年的全因死亡率。采用Cox比例风险模型和Kaplan - Meier生存曲线确定BSS与死亡的相关性,并计算风险比(HR)和95%置信区间(CI)。采用亚组分析确定不同特征人群中BSS与死亡之间的关系。通过筛选,我们将13127例HF患者纳入研究。根据以前的文献和从当前数据计算的敏感性,使用截断值15将参与者分为两个风险组。经cox回归分析排除混杂因素后,中高危组(BSS≤15)患者30天全因死亡率显著高于低危组(校正后HR: 1.732, 95% CI: 1.562 ~ 1.920)。结论:Braden量表评分是ICU老年HF患者30天全因死亡率的重要预测因子。当BSS≤15时,全因死亡率显著增高。此外,压力损伤的发生增加了ICU老年心衰患者全因死亡的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The prognostic value of the Braden scale on all-cause death in older patients with heart failure in the intensive care unit: a cohort study.

Background: Heart failure(HF) remains a major global health challenge associated with high mortality rates.The Braden scale score(BSS) is one of the most commonly used clinical tools to assess a patient's risk of pressure injury, and some studies have reported that it may reflect the patient's frailty status. The aim of this study was to investigate whether the BSS can predict the short- and long-term risk of all-cause mortality in elderly patients with heart failure in the intensive care unit (ICU).

Methods and results: Data from the Medical Information Mart for Intensive Care-IV3.0 (MIMIC-IV 3.0)database for HF patients aged 60 years and older within 24 h of admission were used for this analysis. The required data were extracted, and the data collection period spanned from 2009 to 2023.The primary outcomes for HF patients were 30-day and 1-year all-cause mortality. The Cox proportional hazards model and Kaplan - Meier survival curves were used to determine the association between BSS and death, and Hazard Ratios (HR) and 95% confidence intervals (CI) were calculated. Subgroup analysis was used to determine the association between BSS and death in populations with different characteristics. Through screening, we included 13,127 patients with HF in the study. Based on previous literature and sensitivity calculated from current data, participants were divided into two risk groups using a cutoff value of 15.After cox regression analysis to exclude confounding factors, patients in the medium-to-high-risk group (BSS≤15) had a significantly higher 30-day all-cause mortality rate than those in the low-risk group (corrected HR: 1.732, 95% CI: 1.562 ∼ 1.920, p<0.001).Kaplan-Meier survival curves showed poor 30-day, 90-day, and 180-day outcomes in the medium-high risk group.

Conclusions: The Braden scale score is a significant predictor of 30-day all-cause mortality in elderly HF patients admitted to the ICU. All-cause mortality was significantly higher when the BSS was≤15. Also, the occurrence of pressure injuries increases the risk of all-cause mortality in elderly HF patients in the ICU.

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