一项系统综述:现有文献的显著异质性限制了髋臼周围截骨术治疗髋臼发育不良的研究的适应症和结果的可比性,尽管两者均有改善。

IF 4.4 1区 医学 Q1 ORTHOPEDICS
Benjamin D Kuhns, Nils Becker, Dharma Patel, Paras P Shah, Benjamin G Domb
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引用次数: 0

摘要

目的:本系统综述的目的是报告接受孤立髋臼周围截骨术(PAO)或联合髋关节镜与PAO (PAOHS)手术治疗髋臼发育不良患者的术前和术中变量以及患者报告的结果测量(PROMs)。方法:根据系统评价和荟萃分析的首选报告项目(PRISMA)对文献进行回顾,以确定2014年1月至2025年3月期间发表的报道PAO联合关节镜髋关节手术(PAOHS)或孤立PAO的PROMs的研究。记录患者人口统计学、影像学变量、手术数据以及术后PROMs和并发症。森林样地采用I2统计量鉴定异质性。结果:29项研究(10例PAOHS;19例PAO)共3,809例患者纳入本综述。PAOHS研究的关节内病理发生率为68%-100%。证据等级从1 - 4级不等。PAO和PAOHS研究中最常用的PROMs是改良Harris髋关节评分(mHHS: 53%对70%)和国际髋关节结局工具-12 (iHOT-12;26%对40%),而其他结果评分在两组之间的使用频率更低。所有研究的术后胎膜早破改善均显著,mHHS (I2=0.95)和iHOT-12 (I2=0.97)存在显著异质性。PAOHS组的5项研究报告了临床相关结果,包括最小临床重要差异(MCID)和患者可接受症状状态(PASS),其中MCID率为75.9-93.3%,PASS率为56.4%-91%。在孤立的PAO组中没有关于MCID或PASS的研究报道。结论:虽然PAO和PAOHS都有持续的PROM改善,但两组研究之间存在显著的异质性和可比性,限制了关于关节内干预疗效的潜在结论,尽管PAOHS研究中发现了高水平的关节内病理。证据水平:对1级至4级研究进行系统评价。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Significant Heterogeneity in Existing Literature Limits Both Indication and Outcome Comparability Between Studies Involving Periacetabular Osteotomy For Acetabular Dysplasia With or Without Arthroscopy Despite Improvement for Both: A Systematic Review.

Purpose: The purpose of this systematic review is to report preoperative and intraoperative variables as well as patient-reported outcome measures (PROMs) of patients receiving either isolated periacetabular osteotomy (PAO) or combined hip arthroscopy with PAO (PAOHS) for the surgical management of acetabular dysplasia.

Methods: A review of the literature according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was conducted to identify studies published between January 2014 and March 2025 that reported PROMs for combined arthroscopic hip surgery with PAO (PAOHS) or isolated PAO. Patient demographics, radiographic variables, surgical data, as well as postoperative PROMs and complications were recorded. Forest plots were used to identify heterogeneity using the I2 statistic.

Results: 29 studies (10 PAOHS; 19 PAO) with 3,809 patients were included in the review. Rates of intra-articular pathology for the PAOHS studies ranged from 68%-100%. Level of evidence ranged from I-IV. The most common PROMs used by both the PAO and PAOHS studies were the modified Harris Hip Score (mHHS: 53% vs. 70%) and the International Hip Outcome Tool-12 (iHOT-12; 26% vs. 40%), while other outcome scores were utilized more infrequently between the two groups. Postoperative PROM improvement was significant for all studies with significant heterogeneity for the mHHS (I2=0.95) and iHOT-12 (I2=0.97). Five studies in the PAOHS group reported clinically relevant outcomes including the Minimum Clinically Important Difference (MCID) and Patient Acceptable Symptomatic State (PASS) with MCID rates ranging 75.9-93.3% and PASS rates ranging from 56.4%-91%. No studies in the isolated PAO group reported on the MCID or PASS.

Conclusion: While there was sustained PROM improvement for both the PAO and PAOHS, there was significant heterogeneity and little comparability between the two groups of studies limiting potential conclusions regarding the efficacy of intra-articular intervention despite high levels of intra-articular pathology identified in the PAOHS studies.

Level of evidence: Systematic review of Level I to IV studies.

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来源期刊
CiteScore
9.30
自引率
17.00%
发文量
555
审稿时长
58 days
期刊介绍: Nowhere is minimally invasive surgery explained better than in Arthroscopy, the leading peer-reviewed journal in the field. Every issue enables you to put into perspective the usefulness of the various emerging arthroscopic techniques. The advantages and disadvantages of these methods -- along with their applications in various situations -- are discussed in relation to their efficiency, efficacy and cost benefit. As a special incentive, paid subscribers also receive access to the journal expanded website.
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