水果作为一种预防策略:探索它们在神经退行性疾病管理中的作用。

IF 2.3 Q3 CLINICAL NEUROLOGY
Bhavani Sowndharya B, Rupesh K Gautam, Mathan Muthu C M, Bharath S, Vickram A S, Saravanan A, Gulothungan G, Hitesh Chopra
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引用次数: 0

摘要

水果之所以越来越受欢迎,是因为它们能够预防神经退行性疾病,而且是促进大脑活动的重要饮食成分。这篇综述的重点是考虑到水果的生物活性化合物和作用方式,水果预防这种疾病的潜力。它强调在浆果、柑橘和其他热带水果中发现的丰富的类黄酮、多酚、维生素和矿物质,这些物质已被证明可以减少氧化损伤,预防神经炎症,提高突触可塑性。关于白藜芦醇、槲皮素和花青素等化合物在神经发生和线粒体过程功能中的神经保护作用已有大量文献报道。该评论还提到了有关肠-脑轴的新兴文献,其中强调了水果衍生的益生元和膳食纤维调节肠道微生物群的方式,从而影响大脑健康。本研究通过采用综合方法研究水果在神经退行性疾病治疗中的预防能力来分析差距。这项研究结合了分子生物学、临床试验和饮食科学的发现,强调在日常饮食中使用水果是促进神经保护和减缓ndds进程的一种可持续、自然的方式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fruits as a preventative strategy: exploring their role in neurodegenerative disease management.

Fruits' popularity has grown due to their ability to protect against neurodegenerative illnesses and to be an important dietary component for good brain activity. This review focuses on fruits' potential for preventing such, taking into account their bioactive compounds and mode of action. It emphasizes the abundance of flavonoids, polyphenols, vitamins, and minerals found in berries, citrus, and other tropical fruits, which have been shown to reduce oxidative damage, prevent neuroinflammation, and improve synaptic plasticity. There is an extensive literature on the neuroprotective actions of compounds such as resveratrol, quercetin, and anthocyanins in neurogenesis and mitochondrial process functions. The review also mentions emerging literature with the gut-brain axis, where it underscores the way in which fruit-derived prebiotics and dietary fibers regulate gut microbiota, which in turn affects brain health. This study analyzes gaps by adopting a comprehensive approach to studying fruits' preventive power in the treatment of neurodegenerative illness. This study combines molecular biology, clinical trial, and dietary science findings to highlight the use of fruits in ordinary diets as a sustainable, natural way of promoting neuroprotection and slowing the course of NDs.

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CiteScore
4.30
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