麻疹和实体器官移植：诊断、治疗和预防。

IF 2.6 4区医学 Q3 IMMUNOLOGY

Transplant Infectious Disease Pub Date : 2025-07-01 DOI:10.1111/tid.70066

Stephanie M Pouch, Akshatha Ravindra, Sara W Dong, Wanessa Trindade Clemente, Ricardo M La Hoz, Aaron Mishkin, Jonathan Hand, Maristela Pinheiro Freire, Jacques Simkins, Cameron Wolfe, John W Baddley

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引用次数: 0

摘要

最近，麻疹在国际上卷土重来，引起了重大的公共卫生关切，并对免疫功能低下的患者，包括接受过实体器官移植的患者构成重大风险。SOT接受者可能表现不典型，并且麻疹感染严重并发症的风险增加，强调了预防措施的重要性。这篇综述总结了关于麻疹传播、临床表现、诊断和治疗的当代数据，以及麻疹预防策略、感染控制注意事项、暴露后预防以及减轻供体来源的麻疹和麻疹疫苗病毒的机会。

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Measles and Solid Organ Transplantation: Diagnosis, Treatment, and Prevention.

The recent international resurgence of measles has led to significant public health concerns and poses significant risks to immunocompromised patients, including those who have undergone solid organ transplantation (SOT). SOT recipients may present atypically and are at an increased risk of severe complications of measles infection, underscoring the importance of preventative measures. This review summarizes contemporary data regarding measles transmission, the clinical presentation, diagnosis, and treatment of SOT recipients, as well as strategies for measles prevention, infection control considerations, postexposure prophylaxis, and opportunities for the mitigation of donor-derived measles and measles vaccine viruses.

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来源期刊

Transplant Infectious Disease 医学-传染病学

CiteScore

5.30

自引率

7.70%

发文量

210

审稿时长

4-8 weeks

期刊介绍： Transplant Infectious Disease has been established as a forum for presenting the most current information on the prevention and treatment of infection complicating organ and bone marrow transplantation. The point of view of the journal is that infection and allograft rejection (or graft-versus-host disease) are closely intertwined, and that advances in one area will have immediate consequences on the other. The interaction of the transplant recipient with potential microbial invaders, the impact of immunosuppressive strategies on this interaction, and the effects of cytokines, growth factors, and chemokines liberated during the course of infections, rejection, or graft-versus-host disease are central to the interests and mission of this journal. Transplant Infectious Disease is aimed at disseminating the latest information relevant to the infectious disease complications of transplantation to clinicians and scientists involved in bone marrow, kidney, liver, heart, lung, intestinal, and pancreatic transplantation. The infectious disease consequences and concerns regarding innovative transplant strategies, from novel immunosuppressive agents to xenotransplantation, are very much a concern of this journal. In addition, this journal feels a particular responsibility to inform primary care practitioners in the community, who increasingly are sharing the responsibility for the care of these patients, of the special considerations regarding the prevention and treatment of infection in transplant recipients. As exemplified by the international editorial board, articles are sought throughout the world that address both general issues and those of a more restricted geographic import.