直肠癌患者直肠系膜脂肪组织体积与组织病理学预后关系的研究

IF 3.2 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

European Journal of Radiology Pub Date : 2025-06-28 DOI:10.1016/j.ejrad.2025.112261

Esra Temel , Mustafa Kaya , Leyla Mirzayeva

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引用次数: 0

摘要

目的本研究的目的是探讨内脏脂肪组织（VAT）和直肠系膜脂肪组织（MAT）体积与不良预后因素的关系，包括外静脉侵入（EMVI）和直肠周围脂肪侵入（PFI）。方法回顾性分析2015年1月至2023年12月行腹部盆腔CT检查的直肠癌患者。MAT和VAT体积的定量测量由两名放射科医生利用基于CT的软件程序进行。将测量结果与盆腔磁共振成像（MRI）的组织病理学参数（如外静脉侵入和直肠周围脂肪侵入）进行比较。结果共纳入148例患者（58例，90例）。患者平均年龄59.45±9.97岁。EMVI阳性患者MAT和VAT体积的平均值明显高于EMVI阴性患者(p <；0 05)。此外，发现直肠周围脂肪浸润阳性患者的MAT和VAT体积的平均值明显更高(p <；0.05)。EMVI和PFI阳性患者的体重指数（BMI）也显著升高(p <；0.05)。结论MAT和VAT的体积可能是预测直肠癌预后的重要指标。

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Investigation of the relationship between mesorectal adipose tissue volume measured by computed tomography and histopathological prognostic features in patients with rectal cancer

Purpose

The objective of this study was to examine the correlation between visceral adipose tissue (VAT) and mesorectal adipose tissue (MAT) volumes and poor prognostic factors, including extramural venous invasion (EMVI) and perirectal fat invasion (PFI).

Methods

All patients with rectal cancer who had undergone abdominopelvic computed tomography (CT) from January 2015 to December 2023 were reviewed retrospectively. The quantitative measurement of the MAT and VAT volumes was conducted by two radiologists utilising CT based softwear programme. The measurements were compared with histopathologic parameters such as extramural venous invasion and perirectal fat invasion on pelvic magnetic resonance imaging (MRI).

Results

A total of 148 patients were included in the study (58F, 90 M). The mean age of the patients was 59.45 ± 9.97 years. The mean values of both MAT and VAT volumes were found to be significantly higher in patients with positive EMVI than in those with negative EMVI (p < 0,05). Furthermore, the mean values of both MAT and VAT volumes were found to be significantly higher in patients with positive perirectal fat invasion (p < 0.05). Patients with positive EMVI and PFI also had a significantly higher body mass index (BMI) (p < 0.05).

Conclusion

It may be the case that the volume of MAT and VAT are useful in predicting the prognosis of rectal cancer.

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来源期刊

European Journal of Radiology 医学-核医学

CiteScore

6.70

自引率

3.00%

发文量

398

审稿时长

42 days

期刊介绍： European Journal of Radiology is an international journal which aims to communicate to its readers, state-of-the-art information on imaging developments in the form of high quality original research articles and timely reviews on current developments in the field. Its audience includes clinicians at all levels of training including radiology trainees, newly qualified imaging specialists and the experienced radiologist. Its aim is to inform efficient, appropriate and evidence-based imaging practice to the benefit of patients worldwide.